Metabolic Reprogramming of Breast Tumor-Educated Macrophages Revealed by NMR Metabolomics

Metabolic Reprogramming of Breast Tumor-Educated Macrophages Revealed by NMR Metabolomics

The metabolic crosstalk between tumor cells and tumor-associated macrophages (TAMs) has emerged as a critical contributor to tumor development and progression. In breast cancer (BC), the abundance of immune-suppressive TAMs positively correlates with poor prognosis. However, little is known about ho...

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Bibliographic Details
Main Authors: Ana S. Dias, Catarina R. Almeida, Luisa A. Helguero, Iola F. Duarte
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
breast cancer
tumor microenvironment (TME)
tumor-associated macrophages (TAM)
cell metabolism
metabolic reprogramming
NMR metabolomics
Online Access:https://www.mdpi.com/2072-6694/15/4/1211

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