Dissolving microneedle patch-assisted transdermal delivery of methotrexate improve the therapeutic efficacy of rheumatoid arthritis

Dissolving microneedle patch-assisted transdermal delivery of methotrexate improve the therapeutic efficacy of rheumatoid arthritis

AbstractMethotrexate (MTX) is a first-line treatment for rheumatoid arthritis (RA), but its clinical use is greatly limited by the adverse effects and poor patient compliance caused by traditional oral administration or injection. In recent years, some transdermal drug delivery systems have received...

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Bibliographic Details
Main Authors: Weiman Zhao, Lijie Zheng, Jianhui Yang, Zihui Ma, Xinyi Tao, Qingqing Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Drug Delivery
Subjects:
Dissolving microneedle patch
methotrexate
rheumatoid arthritis
transdermal delivery
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2022.2157518

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