The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP
In plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”. Despite not showing activated defenses, a primed plant induces a more efficient response to recurrent infections. Priming might involve chromat...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Plant Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2023.1133327/full |
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| author | Julián O. Miranda de la Torre Micaela Y. Peppino Margutti Ignacio Lescano López Damián Alejandro Cambiagno Damián Alejandro Cambiagno María E. Alvarez Nicolás M. Cecchini |
| author_facet | Julián O. Miranda de la Torre Micaela Y. Peppino Margutti Ignacio Lescano López Damián Alejandro Cambiagno Damián Alejandro Cambiagno María E. Alvarez Nicolás M. Cecchini |
| author_sort | Julián O. Miranda de la Torre |
| collection | DOAJ |
| description | In plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”. Despite not showing activated defenses, a primed plant induces a more efficient response to recurrent infections. Priming might involve chromatin modifications that allow a faster/stronger activation of defense genes. The Arabidopsis chromatin regulator “Morpheus Molecule 1” (MOM1) has been recently suggested as a priming factor affecting the expression of immune receptor genes. Here, we show that mom1 mutants exacerbate the root growth inhibition response triggered by the key defense priming inducers azelaic acid (AZA), β-aminobutyric acid (BABA) and pipecolic acid (PIP). Conversely, mom1 mutants complemented with a minimal version of MOM1 (miniMOM1 plants) are insensitive. Moreover, miniMOM1 is unable to induce systemic resistance against Pseudomonas sp. in response to these inducers. Importantly, AZA, BABA and PIP treatments reduce the MOM1 expression, but not miniMOM1 transcript levels, in systemic tissues. Consistently, several MOM1-regulated immune receptor genes are upregulated during the activation of systemic resistance in WT plants, while this effect is not observed in miniMOM1. Taken together, our results position MOM1 as a chromatin factor that negatively regulates the defense priming induced by AZA, BABA and PIP. |
| first_indexed | 2024-04-09T13:44:29Z |
| format | Article |
| id | doaj.art-1ee5c21a9a32411fa4b1ac30f13131de |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-04-09T13:44:29Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-1ee5c21a9a32411fa4b1ac30f13131de2023-05-09T05:34:03ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2023-05-011410.3389/fpls.2023.11333271133327The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIPJulián O. Miranda de la Torre0Micaela Y. Peppino Margutti1Ignacio Lescano López2Damián Alejandro Cambiagno3Damián Alejandro Cambiagno4María E. Alvarez5Nicolás M. Cecchini6Centro de Investigaciones en Química Biológica de Córdoba, CIQUIBIC, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Departamento de Química Biológica-Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, ArgentinaCentro de Investigaciones en Química Biológica de Córdoba, CIQUIBIC, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Departamento de Química Biológica-Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, ArgentinaCentro de Investigaciones en Química Biológica de Córdoba, CIQUIBIC, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Departamento de Química Biológica-Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, ArgentinaUnidad de Estudios Agropecuarios (UDEA), Instituto Nacional de Tecnología Agropecuaria (INTA)- Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, ArgentinaDepartamento de Química Biológica-Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, ArgentinaCentro de Investigaciones en Química Biológica de Córdoba, CIQUIBIC, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Departamento de Química Biológica-Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, ArgentinaCentro de Investigaciones en Química Biológica de Córdoba, CIQUIBIC, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Departamento de Química Biológica-Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, ArgentinaIn plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”. Despite not showing activated defenses, a primed plant induces a more efficient response to recurrent infections. Priming might involve chromatin modifications that allow a faster/stronger activation of defense genes. The Arabidopsis chromatin regulator “Morpheus Molecule 1” (MOM1) has been recently suggested as a priming factor affecting the expression of immune receptor genes. Here, we show that mom1 mutants exacerbate the root growth inhibition response triggered by the key defense priming inducers azelaic acid (AZA), β-aminobutyric acid (BABA) and pipecolic acid (PIP). Conversely, mom1 mutants complemented with a minimal version of MOM1 (miniMOM1 plants) are insensitive. Moreover, miniMOM1 is unable to induce systemic resistance against Pseudomonas sp. in response to these inducers. Importantly, AZA, BABA and PIP treatments reduce the MOM1 expression, but not miniMOM1 transcript levels, in systemic tissues. Consistently, several MOM1-regulated immune receptor genes are upregulated during the activation of systemic resistance in WT plants, while this effect is not observed in miniMOM1. Taken together, our results position MOM1 as a chromatin factor that negatively regulates the defense priming induced by AZA, BABA and PIP.https://www.frontiersin.org/articles/10.3389/fpls.2023.1133327/fullArabidopsisazelaic acidpipecolic acidβ-Aminobutyric acidMOM1plant defense |
| spellingShingle | Julián O. Miranda de la Torre Micaela Y. Peppino Margutti Ignacio Lescano López Damián Alejandro Cambiagno Damián Alejandro Cambiagno María E. Alvarez Nicolás M. Cecchini The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP Frontiers in Plant Science Arabidopsis azelaic acid pipecolic acid β-Aminobutyric acid MOM1 plant defense |
| title | The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title_full | The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title_fullStr | The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title_full_unstemmed | The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title_short | The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title_sort | arabidopsis chromatin regulator mom1 is a negative component of the defense priming induced by aza baba and pip |
| topic | Arabidopsis azelaic acid pipecolic acid β-Aminobutyric acid MOM1 plant defense |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2023.1133327/full |
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