Hepatitis B virus infections and risk factors among the general population in Anhui Province, China: an epidemiological study

<p>Abstract</p> <p>Background</p> <p>Hepatitis B is one of the most common infectious diseases in China. The aim of this study was to determine the prevalence of hepatitis B surface antigen (HBsAg) among the general population and the risk factors associated with HBV in...

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Main Authors: Li Xiaoqing, Zheng Yingjun, Liau Adrian, Cai Biao, Ye Dongqing, Huang Feng, Sheng Xiaorong, Ge Fuyang, Xuan Liu, Li Shun, Li Jing
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Public Health
Online Access:http://www.biomedcentral.com/1471-2458/12/272
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author Li Xiaoqing
Zheng Yingjun
Liau Adrian
Cai Biao
Ye Dongqing
Huang Feng
Sheng Xiaorong
Ge Fuyang
Xuan Liu
Li Shun
Li Jing
author_facet Li Xiaoqing
Zheng Yingjun
Liau Adrian
Cai Biao
Ye Dongqing
Huang Feng
Sheng Xiaorong
Ge Fuyang
Xuan Liu
Li Shun
Li Jing
author_sort Li Xiaoqing
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Hepatitis B is one of the most common infectious diseases in China. The aim of this study was to determine the prevalence of hepatitis B surface antigen (HBsAg) among the general population and the risk factors associated with HBV infection in Anhui province, China.</p> <p>Methods</p> <p>A provincial serosurvey was conducted in four cities, and selected through stratified clustering sampling. Data on demographics, immunization history, medical history, family medical history, and life history were collected, along with serum tested for HBsAg. Completed surveys were analysed from 8,875 participants.</p> <p>Results</p> <p>Overall prevalence of HBsAg was 7.44%. Using multivariate analysis, older age was a risk factor for HBsAg infection among children younger than 15 years. Among adults 15-59 years old, the risk factors were male gender, a history of surgical operations, at least one HBsAg-positive family member, and non-vaccination. For adults older than 59 years, the risk factor was a blood transfusion history.</p> <p>Conclusions</p> <p>Though Anhui province has already reached the national goal of reducing HBsAg prevalence to less than 1% among children younger than 5 years, there are still several risk factors for HBsAg infection among the older population. Immunization programs should continue to focus on adults, and interventions should be taken to reduce risk factors associated with being infected with Hepatitis B.</p>
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spelling doaj.art-1ee78a38447148c49e7d0119798de6772022-12-22T01:12:19ZengBMCBMC Public Health1471-24582012-04-0112127210.1186/1471-2458-12-272Hepatitis B virus infections and risk factors among the general population in Anhui Province, China: an epidemiological studyLi XiaoqingZheng YingjunLiau AdrianCai BiaoYe DongqingHuang FengSheng XiaorongGe FuyangXuan LiuLi ShunLi Jing<p>Abstract</p> <p>Background</p> <p>Hepatitis B is one of the most common infectious diseases in China. The aim of this study was to determine the prevalence of hepatitis B surface antigen (HBsAg) among the general population and the risk factors associated with HBV infection in Anhui province, China.</p> <p>Methods</p> <p>A provincial serosurvey was conducted in four cities, and selected through stratified clustering sampling. Data on demographics, immunization history, medical history, family medical history, and life history were collected, along with serum tested for HBsAg. Completed surveys were analysed from 8,875 participants.</p> <p>Results</p> <p>Overall prevalence of HBsAg was 7.44%. Using multivariate analysis, older age was a risk factor for HBsAg infection among children younger than 15 years. Among adults 15-59 years old, the risk factors were male gender, a history of surgical operations, at least one HBsAg-positive family member, and non-vaccination. For adults older than 59 years, the risk factor was a blood transfusion history.</p> <p>Conclusions</p> <p>Though Anhui province has already reached the national goal of reducing HBsAg prevalence to less than 1% among children younger than 5 years, there are still several risk factors for HBsAg infection among the older population. Immunization programs should continue to focus on adults, and interventions should be taken to reduce risk factors associated with being infected with Hepatitis B.</p>http://www.biomedcentral.com/1471-2458/12/272
spellingShingle Li Xiaoqing
Zheng Yingjun
Liau Adrian
Cai Biao
Ye Dongqing
Huang Feng
Sheng Xiaorong
Ge Fuyang
Xuan Liu
Li Shun
Li Jing
Hepatitis B virus infections and risk factors among the general population in Anhui Province, China: an epidemiological study
BMC Public Health
title Hepatitis B virus infections and risk factors among the general population in Anhui Province, China: an epidemiological study
title_full Hepatitis B virus infections and risk factors among the general population in Anhui Province, China: an epidemiological study
title_fullStr Hepatitis B virus infections and risk factors among the general population in Anhui Province, China: an epidemiological study
title_full_unstemmed Hepatitis B virus infections and risk factors among the general population in Anhui Province, China: an epidemiological study
title_short Hepatitis B virus infections and risk factors among the general population in Anhui Province, China: an epidemiological study
title_sort hepatitis b virus infections and risk factors among the general population in anhui province china an epidemiological study
url http://www.biomedcentral.com/1471-2458/12/272
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