DNTTIP1 promotes nasopharyngeal carcinoma metastasis via recruiting HDAC1 to DUSP2 promoter and activating ERK signaling pathway

DNTTIP1 promotes nasopharyngeal carcinoma metastasis via recruiting HDAC1 to DUSP2 promoter and activating ERK signaling pathway

Summary: Background: Distant metastasis remains the leading cause of treatment failure in patients with nasopharyngeal carcinoma (NPC), making it critical to identify efficient therapeutic targets for metastatic NPC. Previous studies have demonstrated that deoxynucleotidyltransferase terminal-inter...

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Bibliographic Details
Main Authors: Shirong Ding, Ying Gao, Dongming Lv, Yalan Tao, Songran Liu, Chen Chen, Zilu Huang, Shuohan Zheng, Yujun Hu, Larry Ka-Yue Chow, Yinghong Wei, Ping Feng, Wei Dai, Xin Wang, Yunfei Xia
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:EBioMedicine
Subjects:
Nasopharyngeal carcinoma
DNTTIP1
DUSP2
ERK signaling pathway
Tumor metastasis
Chidamide
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642200281X

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