Ukrainian Consensus on Diagnosis and Management of Vitamin D Deficiency in Adults
Vitamin D deficiency (VDD) is a global problem, however, there were no Ukrainian guidelines devoted to its screening, prevention, and treatment, which became the reason for the Consensus creation. This article aimed to present the Consensus of Ukrainian experts devoted to VDD management. Following t...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/2/270 |
| _version_ | 1797339461573410816 |
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| author | Nataliia Grygorieva Mykola Tronko Volodymir Kovalenko Serhiy Komisarenko Tetiana Tatarchuk Ninel Dedukh Mykola Veliky Serhiy Strafun Yulia Komisarenko Andrii Kalashnikov Valeria Orlenko Volodymyr Pankiv Oleg Shvets Inna Gogunska Svitlana Regeda |
| author_facet | Nataliia Grygorieva Mykola Tronko Volodymir Kovalenko Serhiy Komisarenko Tetiana Tatarchuk Ninel Dedukh Mykola Veliky Serhiy Strafun Yulia Komisarenko Andrii Kalashnikov Valeria Orlenko Volodymyr Pankiv Oleg Shvets Inna Gogunska Svitlana Regeda |
| author_sort | Nataliia Grygorieva |
| collection | DOAJ |
| description | Vitamin D deficiency (VDD) is a global problem, however, there were no Ukrainian guidelines devoted to its screening, prevention, and treatment, which became the reason for the Consensus creation. This article aimed to present the Consensus of Ukrainian experts devoted to VDD management. Following the creation of the multidisciplinary Consensus group, consent on the formation process, drafting and fine-tuning of key recommendations, and two rounds of voting, 14 final recommendations were successfully voted upon. Despite a recent decrease in VDD prevalence in Ukraine, we recommend raising awareness regarding VDD’s importance and improving the strategies for its decline. We recommend screening the serum 25-hydroxyvitamin D (25(OH)D) level in risk groups while maintaining a target concentration of 75–125 nmol/L (30–50 ng/mL). We recommend prophylactic cholecalciferol supplementation (800–2000 IU/d for youthful healthy subjects, and 3000–5000 IU/d for subjects from the risk groups). For a VDD treatment, we recommend a short-term administration of increased doses of cholecalciferol (4000–10,000 IU/d) with 25(OH)D levels monitored after 4–12 weeks of treatment, followed by the use of maintenance doses. Additionally, we recommend assessing serum 25(OH)D levels before antiosteoporotic treatment and providing vitamin D and calcium supplementation throughout the full course of the antiosteoporotic therapy. |
| first_indexed | 2024-03-08T09:48:28Z |
| format | Article |
| id | doaj.art-1ef1c6e506ec472fb4c0fd792e0bf6bb |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-08T09:48:28Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-1ef1c6e506ec472fb4c0fd792e0bf6bb2024-01-29T14:10:07ZengMDPI AGNutrients2072-66432024-01-0116227010.3390/nu16020270Ukrainian Consensus on Diagnosis and Management of Vitamin D Deficiency in AdultsNataliia Grygorieva0Mykola Tronko1Volodymir Kovalenko2Serhiy Komisarenko3Tetiana Tatarchuk4Ninel Dedukh5Mykola Veliky6Serhiy Strafun7Yulia Komisarenko8Andrii Kalashnikov9Valeria Orlenko10Volodymyr Pankiv11Oleg Shvets12Inna Gogunska13Svitlana Regeda14D.F. Chebotarev Institute of Gerontology, The National Academy of Medical Sciences of Ukraine, 04114 Kyiv, UkraineV.P. Komisarenko Institute of Endocrinology and Metabolism, The National Academy of Medical Sciences of Ukraine, 04114 Kyiv, UkraineNational Scientific Center «The M.D. Strazhesko Institute of Cardiology», Clinical and Regenerative Medicine, The National Academy of Medical Sciences of Ukraine, 03151 Kyiv, UkrainePalladin Institute of Biochemistry, The National Academy of Sciences of Ukraine, 02000 Kyiv, UkraineInstitute of Pediatrics, Obstetrics and Gynecology Named after Academician O.M. Lukyanova, The National Academy of Medical Sciences of Ukraine, 04050 Kyiv, UkraineD.F. Chebotarev Institute of Gerontology, The National Academy of Medical Sciences of Ukraine, 04114 Kyiv, UkrainePalladin Institute of Biochemistry, The National Academy of Sciences of Ukraine, 02000 Kyiv, UkraineInstitute of Traumatology and Orthopedics, The National Academy of Medical Sciences of Ukraine, 01601 Kyiv, UkraineDepartment of Endocrinology, O.O. Bogomolets National Medical University, 01601 Kyiv, UkraineInstitute of Traumatology and Orthopedics, The National Academy of Medical Sciences of Ukraine, 01601 Kyiv, UkraineV.P. Komisarenko Institute of Endocrinology and Metabolism, The National Academy of Medical Sciences of Ukraine, 04114 Kyiv, UkraineUkrainian Scientific and Practical Centre for Endocrine Surgery, Transplantation of Endocrine Organs and Tissues, Health Ministry of Ukraine, 01021 Kyiv, UkraineDepartment of Public Health and Nutrition, National University of Life and Environmental Sciences of Ukraine, 03041 Kyiv, UkraineO.S. Kolomiychenko Institute of Otolaryngology, The National Academy of Medical Sciences of Ukraine, 03057 Kyiv, UkraineCenter of Innovative Medical Technologies, The National Academy of Sciences of Ukraine, 04053 Kyiv, UkraineVitamin D deficiency (VDD) is a global problem, however, there were no Ukrainian guidelines devoted to its screening, prevention, and treatment, which became the reason for the Consensus creation. This article aimed to present the Consensus of Ukrainian experts devoted to VDD management. Following the creation of the multidisciplinary Consensus group, consent on the formation process, drafting and fine-tuning of key recommendations, and two rounds of voting, 14 final recommendations were successfully voted upon. Despite a recent decrease in VDD prevalence in Ukraine, we recommend raising awareness regarding VDD’s importance and improving the strategies for its decline. We recommend screening the serum 25-hydroxyvitamin D (25(OH)D) level in risk groups while maintaining a target concentration of 75–125 nmol/L (30–50 ng/mL). We recommend prophylactic cholecalciferol supplementation (800–2000 IU/d for youthful healthy subjects, and 3000–5000 IU/d for subjects from the risk groups). For a VDD treatment, we recommend a short-term administration of increased doses of cholecalciferol (4000–10,000 IU/d) with 25(OH)D levels monitored after 4–12 weeks of treatment, followed by the use of maintenance doses. Additionally, we recommend assessing serum 25(OH)D levels before antiosteoporotic treatment and providing vitamin D and calcium supplementation throughout the full course of the antiosteoporotic therapy.https://www.mdpi.com/2072-6643/16/2/270Consensusdeficiencypreventionrecommendationsscreeningsupplementation |
| spellingShingle | Nataliia Grygorieva Mykola Tronko Volodymir Kovalenko Serhiy Komisarenko Tetiana Tatarchuk Ninel Dedukh Mykola Veliky Serhiy Strafun Yulia Komisarenko Andrii Kalashnikov Valeria Orlenko Volodymyr Pankiv Oleg Shvets Inna Gogunska Svitlana Regeda Ukrainian Consensus on Diagnosis and Management of Vitamin D Deficiency in Adults Nutrients Consensus deficiency prevention recommendations screening supplementation |
| title | Ukrainian Consensus on Diagnosis and Management of Vitamin D Deficiency in Adults |
| title_full | Ukrainian Consensus on Diagnosis and Management of Vitamin D Deficiency in Adults |
| title_fullStr | Ukrainian Consensus on Diagnosis and Management of Vitamin D Deficiency in Adults |
| title_full_unstemmed | Ukrainian Consensus on Diagnosis and Management of Vitamin D Deficiency in Adults |
| title_short | Ukrainian Consensus on Diagnosis and Management of Vitamin D Deficiency in Adults |
| title_sort | ukrainian consensus on diagnosis and management of vitamin d deficiency in adults |
| topic | Consensus deficiency prevention recommendations screening supplementation |
| url | https://www.mdpi.com/2072-6643/16/2/270 |
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