PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C

PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C

Summary: Alternative splicing (AS) has been implicated in cell cycle regulation and cancer, but the underlying mechanisms are poorly understood. The poly(U)-binding splicing factor 60 (PUF60) is essential for embryonic development and is overexpressed in multiple types of cancer. Here, we report tha...

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Bibliographic Details
Main Authors: Nan Xu, Yunpeng Ren, Yufang Bao, Xianfeng Shen, Jiahui Kang, Ning Wang, Zixian Wang, Xinlu Han, Zhen Li, Ji Zuo, Gong-Hong Wei, Zefeng Wang, Wei-Xing Zong, Wen Liu, Gangcai Xie, Yongbo Wang
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723010525

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