Polygenic heterogeneity in antidepressant treatment and placebo response

Abstract The genetic architecture of antidepressant response is poorly understood. Polygenic risk scores (PRS), exploration of placebo response and the use of sub-scales might provide insights. Here, we investigate the association between PRSs for relevant complex traits and response to vortioxetine...

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Bibliographic Details
Main Authors: Anne Krogh Nøhr, Annika Forsingdal, Ida Moltke, Oliver D. Howes, Morana Vitezic, Anders Albrechtsen, Maria Dalby
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02221-4