Polygenic heterogeneity in antidepressant treatment and placebo response
Abstract The genetic architecture of antidepressant response is poorly understood. Polygenic risk scores (PRS), exploration of placebo response and the use of sub-scales might provide insights. Here, we investigate the association between PRSs for relevant complex traits and response to vortioxetine...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-10-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-022-02221-4 |