Cognitive and behavioral improvement in adults with fragile X syndrome treated with metformin‐two cases

Cognitive and behavioral improvement in adults with fragile X syndrome treated with metformin‐two cases

Abstract Background The majority of individuals with fragile X syndrome (FXS) have intellectual disability, behavioral problems, autism, and language deficits. IQ typically declines with age in boys with the full mutation. The results of preclinical studies demonstrated that metformin, a biguanide u...

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Bibliographic Details
Main Authors: Dragana Protic, Elber Y. Aydin, Flora Tassone, Maria M. Tan, Randi J. Hagerman, Andrea Schneider
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
cognition improvement
fragile X syndrome
metformin
targeted treatment
Online Access:https://doi.org/10.1002/mgg3.745

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