Aberrant expression of COL4A1 in age-related cataract and its effect on cell proliferation, apoptosis and gene expression changes
AIM: To evaluate the regulation of the aberrant expression of collagen type IV alpha 1 chain (COL4A1) in the development of age-related cataract (ARC). METHODS: Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and Western blot analysis were employed to evaluate the expression o...
Main Authors: | Dan Zhu, Peng Li, Li Wang, Yuan He, Hui-Zi Zhang |
---|---|
Format: | Article |
Language: | English |
Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2023-03-01
|
Series: | International Journal of Ophthalmology |
Subjects: | |
Online Access: | http://ies.ijo.cn/en_publish/2023/3/20230301.pdf |
Similar Items
-
DNA hypermethylation of COL4A1 in ultraviolet-B-induced age-related cataract models in vitro and in vivo
by: Li Wang, et al.
Published: (2024-10-01) -
High-expression of ROCK1 modulates the apoptosis of lens epithelial cells in age-related cataracts by targeting p53 gene
by: Shanshan Hu, et al.
Published: (2020-12-01) -
Severe Abnormalities of Lens Epithelial Cells in Exfoliation Syndrome: A Transmission Electron Microscopy Study of Patients with Age-Related Cataract
by: Konstantina Ν. Sorkou, et al.
Published: (2019-05-01) -
A lipidomic study on the lens epithelial cells of patients with age related cataracts
by: Yingying Gong, et al.
Published: (2024-09-01) -
Physical activity and risk of age-related cataract
by: Hong Jiang, et al.
Published: (2020-04-01)