The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal Intubating
Abstract Background and purpose: Neuromuscular relaxants are one group of the important drugs in providing good condition for tracheal intubation and operation. Rapid intubation is needed in most situations. Also, most of non- depolarizing relaxants almost have long onset time. We compared the primi...
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| Language: | English |
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Mazandaran University of Medical Sciences
2007-01-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
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| Online Access: | http://www.mazums.ac.ir/files/onlineJournals_2176005=parish.pdf |
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| author | S. Sanaie, M.D ** N. Gharahdaghi, M.D. A. Mahmoodpoor, M.D M. Parish, M.D. +. |
| author_facet | S. Sanaie, M.D ** N. Gharahdaghi, M.D. A. Mahmoodpoor, M.D M. Parish, M.D. +. |
| author_sort | S. Sanaie, M.D |
| collection | DOAJ |
| description | Abstract Background and purpose: Neuromuscular relaxants are one group of the important drugs in providing good condition for tracheal intubation and operation. Rapid intubation is needed in most situations. Also, most of non- depolarizing relaxants almost have long onset time. We compared the priming with pancrunium and atracurium in providing good and rapid relaxation for tracheal intubation.Materials and Methods: In this prospective study, 65 patients with ASA class I, II were randomized into two groups. Group A received pancrunium and group B received atracurium. Primimg dose was injected as 20% of total dose of relaxant. Twitching response was measured with peripheral nerve stimulator. Intubation was done when % 80 of the twitching response disappeared. The time of total disappearance of twitching response was also recorded.Results: The mean time for the injection of the first dose of relaxant until the time of intubation was 94.47 seconds in group A and 142.9 seconds in group B, which were significantly different (P<0/01). If intubation until the time of twitch response is detained, the time gap of group A will again be less than group B (P<0/01).Conclusion: In priming technique, the time of tracheal intubation with pancrunium is significantly less than atracurium. So, considering the patient's condition and the need for rapid relaxation, pancrunium could be is a better relaxant than atracurium. |
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| institution | Directory Open Access Journal |
| issn | 1735-9260 |
| language | English |
| last_indexed | 2024-12-10T15:13:06Z |
| publishDate | 2007-01-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-1efa19bed12b4e73a4a4a101df66a22e2022-12-22T01:43:52ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92602007-01-0117583742The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal IntubatingS. Sanaie, M.D** N. Gharahdaghi, M.D.A. Mahmoodpoor, M.DM. Parish, M.D. +.Abstract Background and purpose: Neuromuscular relaxants are one group of the important drugs in providing good condition for tracheal intubation and operation. Rapid intubation is needed in most situations. Also, most of non- depolarizing relaxants almost have long onset time. We compared the priming with pancrunium and atracurium in providing good and rapid relaxation for tracheal intubation.Materials and Methods: In this prospective study, 65 patients with ASA class I, II were randomized into two groups. Group A received pancrunium and group B received atracurium. Primimg dose was injected as 20% of total dose of relaxant. Twitching response was measured with peripheral nerve stimulator. Intubation was done when % 80 of the twitching response disappeared. The time of total disappearance of twitching response was also recorded.Results: The mean time for the injection of the first dose of relaxant until the time of intubation was 94.47 seconds in group A and 142.9 seconds in group B, which were significantly different (P<0/01). If intubation until the time of twitch response is detained, the time gap of group A will again be less than group B (P<0/01).Conclusion: In priming technique, the time of tracheal intubation with pancrunium is significantly less than atracurium. So, considering the patient's condition and the need for rapid relaxation, pancrunium could be is a better relaxant than atracurium.http://www.mazums.ac.ir/files/onlineJournals_2176005=parish.pdfPancruniumAtracuriumPrimingTracheal intubation |
| spellingShingle | S. Sanaie, M.D ** N. Gharahdaghi, M.D. A. Mahmoodpoor, M.D M. Parish, M.D. +. The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal Intubating Journal of Mazandaran University of Medical Sciences Pancrunium Atracurium Priming Tracheal intubation |
| title | The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal Intubating |
| title_full | The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal Intubating |
| title_fullStr | The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal Intubating |
| title_full_unstemmed | The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal Intubating |
| title_short | The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal Intubating |
| title_sort | comparison of priming with pancrunium and atracurium in the speed of providing adequate neuromuscular blockade for tracheal intubating |
| topic | Pancrunium Atracurium Priming Tracheal intubation |
| url | http://www.mazums.ac.ir/files/onlineJournals_2176005=parish.pdf |
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