Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia

Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by low platelet counts. First-line treatment includes intravenous immunoglobulin (IVIg), however, its working mechanism remains incompletely understood. We investigated splenic and thymic dendritic cell (DC) subsets upon...

Full description

Bibliographic Details
Main Authors: Rick Kapur, Rukhsana Aslam, Michael Kim, Li Guo, Heyu Ni, George B. Segel, John W. Semple
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:Platelets
Subjects:
ivig
dendritic cells
immune thrombocytopenia
Online Access:http://dx.doi.org/10.1080/09537104.2016.1246718

Internet

http://dx.doi.org/10.1080/09537104.2016.1246718

Similar Items