Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia

Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by low platelet counts. First-line treatment includes intravenous immunoglobulin (IVIg), however, its working mechanism remains incompletely understood. We investigated splenic and thymic dendritic cell (DC) subsets upon...

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Bibliographic Details
Main Authors:	Rick Kapur, Rukhsana Aslam, Michael Kim, Li Guo, Heyu Ni, George B. Segel, John W. Semple
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2017-07-01
Series:	Platelets
Subjects:	ivig dendritic cells immune thrombocytopenia
Online Access:	http://dx.doi.org/10.1080/09537104.2016.1246718

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