Dengue virus co-opts innate type 2 pathways to escape early control of viral replication

Dengue virus co-opts innate type 2 pathways to escape early control of viral replication

Group 2 innate lymphoid cells are activated during acute dengue viral infection in human, downregulate type I-IFN responsive gene and protein expression through Prostaglandin D2, and are permissive for productive dengue viral infection.

Bibliographic Details
Main Authors: Chathuranga L. Fonseka, Clare S. Hardman, Jeongmin. Woo, Randeep Singh, Janina Nahler, Jiahe Yang, Yi-Ling Chen, Achala Kamaladasa, Tehani Silva, Maryam Salimi, Nicki Gray, Tao Dong, Gathsaurie N. Malavige, Graham S. Ogg
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03682-5

Internet

https://doi.org/10.1038/s42003-022-03682-5

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