Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions
Background/Aims Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) remains the most common EUS-guided tissue acquisition technique. This study aimed to evaluate the performance of a new Franseen tip fine needle biopsy (FNB) device for EUSguided sampling of solid lesions and compare it wit...
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| Format: | Article |
| Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2018-11-01
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| Series: | Clinical Endoscopy |
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| Online Access: | http://www.e-ce.org/upload/pdf/ce-2018-053.pdf |
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| author | Ihab I. El Hajj Howard Wu Sarah Reuss Melissa Randolph Akeem Harris Mark A. Gromski Mohammad Al-Haddad |
| author_facet | Ihab I. El Hajj Howard Wu Sarah Reuss Melissa Randolph Akeem Harris Mark A. Gromski Mohammad Al-Haddad |
| author_sort | Ihab I. El Hajj |
| collection | DOAJ |
| description | Background/Aims Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) remains the most common EUS-guided tissue acquisition technique. This study aimed to evaluate the performance of a new Franseen tip fine needle biopsy (FNB) device for EUSguided sampling of solid lesions and compare it with the historical FNA technique. Methods Acquire® 22 G FNB needle (Boston Scientific Co., Natick, MA, USA) was used for solid tumor sampling (Study group). Tissue was collected for rapid on-site evaluation, and touch and crush preparations were made. Historical EUS-FNA samples obtained using Expect® 22 G FNA needle (Boston Scientific Co.) were used as controls (Control group). All specimens were independently evaluated by two cytopathologists blinded to the formal cytopathological diagnosis. Results Mean cell block histology scores were significantly higher (p=0.046) in the FNB group (51 samples) despite a significantly lower (p<0.001) mean number of passes compared to the FNA group (50 specimens). The overall diagnostic yields for the FNB vs. FNA groups were 96% vs. 88%. The degree of tumor differentiation was adequately assessed in all cell block qualifying lesions in the FNB group. Two patients developed post-FNB abdominal pain. Conclusions The new Franseen tip FNB device provides histologically superior and cytologically comparable specimens to those obtained by FNA, but with fewer passes. |
| first_indexed | 2024-03-11T20:42:06Z |
| format | Article |
| id | doaj.art-1f09bc4330ff4940885fcbb1181ec275 |
| institution | Directory Open Access Journal |
| issn | 2234-2400 2234-2443 |
| language | English |
| last_indexed | 2024-03-11T20:42:06Z |
| publishDate | 2018-11-01 |
| publisher | Korean Society of Gastrointestinal Endoscopy |
| record_format | Article |
| series | Clinical Endoscopy |
| spelling | doaj.art-1f09bc4330ff4940885fcbb1181ec2752023-10-02T00:58:54ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432018-11-0151657658310.5946/ce.2018.0537117Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid LesionsIhab I. El Hajj0Howard Wu1Sarah Reuss2Melissa Randolph3Akeem Harris4Mark A. Gromski5Mohammad Al-Haddad6 Division of Gastroenterology, Section of Interventional Endoscopy, Indiana University School of Medicine, Indianapolis, IN, USA Department of Laboratory Medicine and Cytopathology, Indiana University School of Medicine, Indianapolis, IN, USA Department of Laboratory Medicine and Cytopathology, Indiana University School of Medicine, Indianapolis, IN, USA Department of Laboratory Medicine and Cytopathology, Indiana University School of Medicine, Indianapolis, IN, USA Department of Laboratory Medicine and Cytopathology, Indiana University School of Medicine, Indianapolis, IN, USA Division of Gastroenterology, Section of Interventional Endoscopy, Indiana University School of Medicine, Indianapolis, IN, USA Division of Gastroenterology, Section of Interventional Endoscopy, Indiana University School of Medicine, Indianapolis, IN, USABackground/Aims Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) remains the most common EUS-guided tissue acquisition technique. This study aimed to evaluate the performance of a new Franseen tip fine needle biopsy (FNB) device for EUSguided sampling of solid lesions and compare it with the historical FNA technique. Methods Acquire® 22 G FNB needle (Boston Scientific Co., Natick, MA, USA) was used for solid tumor sampling (Study group). Tissue was collected for rapid on-site evaluation, and touch and crush preparations were made. Historical EUS-FNA samples obtained using Expect® 22 G FNA needle (Boston Scientific Co.) were used as controls (Control group). All specimens were independently evaluated by two cytopathologists blinded to the formal cytopathological diagnosis. Results Mean cell block histology scores were significantly higher (p=0.046) in the FNB group (51 samples) despite a significantly lower (p<0.001) mean number of passes compared to the FNA group (50 specimens). The overall diagnostic yields for the FNB vs. FNA groups were 96% vs. 88%. The degree of tumor differentiation was adequately assessed in all cell block qualifying lesions in the FNB group. Two patients developed post-FNB abdominal pain. Conclusions The new Franseen tip FNB device provides histologically superior and cytologically comparable specimens to those obtained by FNA, but with fewer passes.http://www.e-ce.org/upload/pdf/ce-2018-053.pdfTissue acquisitionEndoscopic ultrasound-guided fine needle aspirationEndoscopic ultrasound-guided fine needle biopsy |
| spellingShingle | Ihab I. El Hajj Howard Wu Sarah Reuss Melissa Randolph Akeem Harris Mark A. Gromski Mohammad Al-Haddad Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions Clinical Endoscopy Tissue acquisition Endoscopic ultrasound-guided fine needle aspiration Endoscopic ultrasound-guided fine needle biopsy |
| title | Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions |
| title_full | Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions |
| title_fullStr | Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions |
| title_full_unstemmed | Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions |
| title_short | Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions |
| title_sort | prospective assessment of the performance of a new fine needle biopsy device for eus guided sampling of solid lesions |
| topic | Tissue acquisition Endoscopic ultrasound-guided fine needle aspiration Endoscopic ultrasound-guided fine needle biopsy |
| url | http://www.e-ce.org/upload/pdf/ce-2018-053.pdf |
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