Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report
Haci Bayram Tosun,1 Sancar Serbest,2 Bilge Aydin Turk,3 Seyit Ali Gumustas,1 Abuzer Uludag1 1Department of Orthopaedics and Traumatology, Faculty of Medicine, Adiyaman University, Adiyaman, 2Department of Orthopaedics and Traumatology, Faculty of Medicine, Kirikkale University, Kirikkale, 3Departmen...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2015-10-01
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| Series: | International Medical Case Reports Journal |
| Online Access: | https://www.dovepress.com/giant-malignant-peripheral-nerve-sheath-tumor-of-thigh-in-an-adolescen-peer-reviewed-article-IMCRJ |
| _version_ | 1811303972330274816 |
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| author | Tosun HB Serbest S Turk BA Gumustas SA Uludag A |
| author_facet | Tosun HB Serbest S Turk BA Gumustas SA Uludag A |
| author_sort | Tosun HB |
| collection | DOAJ |
| description | Haci Bayram Tosun,1 Sancar Serbest,2 Bilge Aydin Turk,3 Seyit Ali Gumustas,1 Abuzer Uludag1 1Department of Orthopaedics and Traumatology, Faculty of Medicine, Adiyaman University, Adiyaman, 2Department of Orthopaedics and Traumatology, Faculty of Medicine, Kirikkale University, Kirikkale, 3Department of Pathology, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey Abstract: Malignant peripheral nerve sheath tumors (MPNSTs) are rare sarcomas of children and adolescents, and they are aggressive tumors with a high rate of local recurrence. We present a 15-year-old boy with neurofibromatosis type 1 (NF1), who had a giant MPNST on the right thigh taking into account the available literature. Diagnosis of MPNST may be delayed in NF1 patients due to confusion with a neurofibroma and/or a plexiform neurofibroma. Malignancy should be considered, especially in cases with big masses, with heterogeneous involvement, or in the presence of cysts or necrotic nodules. The aim of surgical treatment is complete surgical excision. Keywords: nerve sheath neoplasm, sarcoma, adolescent, neurofibromatosis, lower extremity |
| first_indexed | 2024-04-13T07:57:41Z |
| format | Article |
| id | doaj.art-1f0b179dfcb642caa643e01a5de781ba |
| institution | Directory Open Access Journal |
| issn | 1179-142X |
| language | English |
| last_indexed | 2024-04-13T07:57:41Z |
| publishDate | 2015-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj.art-1f0b179dfcb642caa643e01a5de781ba2022-12-22T02:55:21ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2015-10-012015default26727124343Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case reportTosun HBSerbest STurk BAGumustas SAUludag AHaci Bayram Tosun,1 Sancar Serbest,2 Bilge Aydin Turk,3 Seyit Ali Gumustas,1 Abuzer Uludag1 1Department of Orthopaedics and Traumatology, Faculty of Medicine, Adiyaman University, Adiyaman, 2Department of Orthopaedics and Traumatology, Faculty of Medicine, Kirikkale University, Kirikkale, 3Department of Pathology, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey Abstract: Malignant peripheral nerve sheath tumors (MPNSTs) are rare sarcomas of children and adolescents, and they are aggressive tumors with a high rate of local recurrence. We present a 15-year-old boy with neurofibromatosis type 1 (NF1), who had a giant MPNST on the right thigh taking into account the available literature. Diagnosis of MPNST may be delayed in NF1 patients due to confusion with a neurofibroma and/or a plexiform neurofibroma. Malignancy should be considered, especially in cases with big masses, with heterogeneous involvement, or in the presence of cysts or necrotic nodules. The aim of surgical treatment is complete surgical excision. Keywords: nerve sheath neoplasm, sarcoma, adolescent, neurofibromatosis, lower extremityhttps://www.dovepress.com/giant-malignant-peripheral-nerve-sheath-tumor-of-thigh-in-an-adolescen-peer-reviewed-article-IMCRJ |
| spellingShingle | Tosun HB Serbest S Turk BA Gumustas SA Uludag A Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report International Medical Case Reports Journal |
| title | Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
| title_full | Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
| title_fullStr | Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
| title_full_unstemmed | Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
| title_short | Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
| title_sort | giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1 a case report |
| url | https://www.dovepress.com/giant-malignant-peripheral-nerve-sheath-tumor-of-thigh-in-an-adolescen-peer-reviewed-article-IMCRJ |
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