Cold-Inducible RNA-Binding Protein but Not Its Antisense lncRNA Is a Direct Negative Regulator of Angiogenesis In Vitro and In Vivo via Regulation of the 14q32 angiomiRs—microRNA-329-3p and microRNA-495-3p

Cold-Inducible RNA-Binding Protein but Not Its Antisense lncRNA Is a Direct Negative Regulator of Angiogenesis In Vitro and In Vivo via Regulation of the 14q32 angiomiRs—microRNA-329-3p and microRNA-495-3p

Inhibition of the 14q32 microRNAs, miR-329-3p and miR-495-3p, improves post-ischemic neovascularization. Cold-inducible RNA-binding protein (<i>CIRBP</i>) facilitates maturation of these microRNAs. We hypothesized that <i>CIRBP</i> deficiency improves post-ischemic angiogenes...

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Bibliographic Details
Main Authors: Eveline A. C. Goossens, Licheng Zhang, Margreet R. de Vries, J. Wouter Jukema, Paul H. A. Quax, A. Yaël Nossent
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
<i>CIRBP</i>
14q32 microRNAs
angiogenesis
peripheral arterial disease
HUVECs
Online Access:https://www.mdpi.com/1422-0067/22/23/12678

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