Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene.

Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene.

The proopiomelanocortin gene (POMC) is expressed in the pituitary gland and the ventral hypothalamus of all jawed vertebrates, producing several bioactive peptides that function as peripheral hormones or central neuropeptides, respectively. We have recently determined that mouse and human POMC expre...

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Bibliographic Details
Main Authors: Andrea M Santangelo, Flávio S J de Souza, Lucía F Franchini, Viviana F Bumaschny, Malcolm J Low, Marcelo Rubinstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2000970?pdf=render

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