Transplant of microbiota from Crohn’s disease patients to germ-free mice results in colitis

Transplant of microbiota from Crohn’s disease patients to germ-free mice results in colitis

ABSTRACTAlthough the role of the intestinal microbiota in the pathogenesis of inflammatory bowel disease (IBD) is beyond debate, attempts to verify the causative role of IBD-associated dysbiosis have been limited to reports of promoting the disease in genetically susceptible mice or in chemically in...

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Bibliographic Details
Main Authors: Irshad Ali Sheikh, Jared Bianchi-Smak, Daniel Laubitz, Gabriele Schiro, Monica T. Midura-Kiela, David G. Besselsen, Gayatri Vedantam, Sara Jarmakiewicz, Rafał Filip, Fayez K. Ghishan, Nan Gao, Pawel R. Kiela
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Gut Microbes
Subjects:
Crohn’s ileocolitis
microbiota
fecal microbiome transplant
germ-free mice
inflammation
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2024.2333483

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