False-positive 18-fluorodeoxyglucose positron emission tomography–computed tomography (FDG PET/CT) scans mimicking malignancies
Aim 18-Fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET/CT) is an imaging modality that is often used to help differentiate benign from malignant pulmonary lesions and it has been shown to be more efficacious than conventional chest computed tomography (CT). However, so...
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| Format: | Article |
| Language: | English |
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Medical Association of Zenica-Doboj Canton
2015-02-01
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| Series: | Medicinski Glasnik |
| Subjects: | |
| Online Access: | http://www.ljkzedo.ba/sites/default/files/Glasnik/12-01-feb2015/06%20Yasar.pdf |
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| author | Zehra Yasar Murat Acat Hilal Onaran Akif Ozgül Erhan H. Dincer Erdogan Cetinkaya Nurdan A. Korkmaz |
| author_facet | Zehra Yasar Murat Acat Hilal Onaran Akif Ozgül Erhan H. Dincer Erdogan Cetinkaya Nurdan A. Korkmaz |
| author_sort | Zehra Yasar |
| collection | DOAJ |
| description | Aim 18-Fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET/CT) is an imaging modality that is often used to help differentiate benign from malignant pulmonary lesions and it has been shown to be more efficacious than conventional chest computed tomography (CT). However, some benign lesions may also show increased metabolic activity which can lead to false-positive PET findings. We aim to illustrate false positive findings of PET scan that simulate lung cancer in a variety of diseases.
Methods Patients referred to Yedikule Chest Diseases and Surgery Teaching and Research Hospital with increased FDG uptake for which histological results were available over a 2-year period (2013-2014) were reviewed. Seven patients with false-positive PET/CT findings were reported in this study.
Results The majority of lesions showing increased metabolic activity were due to malignant diseases. However, increased 18 F-FDG uptake was also seen in benign lesions such as active pulmonary inflammation or infection, granulomatous processes and fibrotic lesions.
Conclusion. The integration of clinical history, morphologic findings of lesions on the CT component, and metabolic activities of PET/CT scan can help reduce false interpretations. Interventional procedures. |
| first_indexed | 2024-12-11T05:46:29Z |
| format | Article |
| id | doaj.art-1f18c11f169d43ee9febb903cf7d8a40 |
| institution | Directory Open Access Journal |
| issn | 1840-0132 1840-2445 |
| language | English |
| last_indexed | 2024-12-11T05:46:29Z |
| publishDate | 2015-02-01 |
| publisher | Medical Association of Zenica-Doboj Canton |
| record_format | Article |
| series | Medicinski Glasnik |
| spelling | doaj.art-1f18c11f169d43ee9febb903cf7d8a402022-12-22T01:18:57ZengMedical Association of Zenica-Doboj CantonMedicinski Glasnik1840-01321840-24452015-02-011214046False-positive 18-fluorodeoxyglucose positron emission tomography–computed tomography (FDG PET/CT) scans mimicking malignanciesZehra Yasar0Murat Acat1Hilal Onaran2Akif Ozgül3Erhan H. Dincer4Erdogan Cetinkaya5Nurdan A. Korkmaz6Department of Chest Diseases, School of Medicine, Abant Izzet Baysal University, Bolu, TurkeyDepartment of Chest Diseases, School of Medicine, Karabuk University, Karabuk, TurkeyPulmonary Division, Yedikule Chest Diseases and Surgery Teaching and Research Hospital, Istanbul, TurkeyPulmonary Division, Yedikule Chest Diseases and Surgery Teaching and Research Hospital, Istanbul, TurkeyDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Minnesota, MN, USAPulmonary Division, Yedikule Chest Diseases and Surgery Teaching and Research Hospital, Istanbul, TurkeyDepartment of Nuclear Medicine, School of Medicine, Abant Izzet Baysal University, Bolu, TurkeyAim 18-Fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET/CT) is an imaging modality that is often used to help differentiate benign from malignant pulmonary lesions and it has been shown to be more efficacious than conventional chest computed tomography (CT). However, some benign lesions may also show increased metabolic activity which can lead to false-positive PET findings. We aim to illustrate false positive findings of PET scan that simulate lung cancer in a variety of diseases. Methods Patients referred to Yedikule Chest Diseases and Surgery Teaching and Research Hospital with increased FDG uptake for which histological results were available over a 2-year period (2013-2014) were reviewed. Seven patients with false-positive PET/CT findings were reported in this study. Results The majority of lesions showing increased metabolic activity were due to malignant diseases. However, increased 18 F-FDG uptake was also seen in benign lesions such as active pulmonary inflammation or infection, granulomatous processes and fibrotic lesions. Conclusion. The integration of clinical history, morphologic findings of lesions on the CT component, and metabolic activities of PET/CT scan can help reduce false interpretations. Interventional procedures.http://www.ljkzedo.ba/sites/default/files/Glasnik/12-01-feb2015/06%20Yasar.pdffalse –positiveFDGPET scanmimicking malignancies |
| spellingShingle | Zehra Yasar Murat Acat Hilal Onaran Akif Ozgül Erhan H. Dincer Erdogan Cetinkaya Nurdan A. Korkmaz False-positive 18-fluorodeoxyglucose positron emission tomography–computed tomography (FDG PET/CT) scans mimicking malignancies Medicinski Glasnik false –positive FDG PET scan mimicking malignancies |
| title | False-positive 18-fluorodeoxyglucose positron emission tomography–computed tomography (FDG PET/CT) scans mimicking malignancies |
| title_full | False-positive 18-fluorodeoxyglucose positron emission tomography–computed tomography (FDG PET/CT) scans mimicking malignancies |
| title_fullStr | False-positive 18-fluorodeoxyglucose positron emission tomography–computed tomography (FDG PET/CT) scans mimicking malignancies |
| title_full_unstemmed | False-positive 18-fluorodeoxyglucose positron emission tomography–computed tomography (FDG PET/CT) scans mimicking malignancies |
| title_short | False-positive 18-fluorodeoxyglucose positron emission tomography–computed tomography (FDG PET/CT) scans mimicking malignancies |
| title_sort | false positive 18 fluorodeoxyglucose positron emission tomography computed tomography fdg pet ct scans mimicking malignancies |
| topic | false –positive FDG PET scan mimicking malignancies |
| url | http://www.ljkzedo.ba/sites/default/files/Glasnik/12-01-feb2015/06%20Yasar.pdf |
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