Inhibiting uptake of extracellular vesicles derived from senescent bone marrow mesenchymal stem cells by muscle satellite cells attenuates sarcopenia
Objective: Osteoporosis is associated with senescence of bone marrow mesenchymal stem cells (BMSCs). Extracellular vesicles derived from senescent BMSCs (BMSC-EVs) could be uptaken by muscle satellite cells (SCs). We hypothesized that inhibiting the uptake of harmful BMSC-EVs by SCs could prevent pa...
Main Authors: | Hanhao Dai, Wu Zheng, Jun Luo, Guoyu Yu, Chao Song, Yijing Wu, Jie Xu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-07-01
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Series: | Journal of Orthopaedic Translation |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214031X22000523 |
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