A new e-health cloud-based system for cardiovascular risk assessment

Sudden cardiac death (SCD) is one of the leading causes of death worldwide. Many individuals have no cardiovascular symptoms before the SCD event. As a result, the ability to identify the risk before such an event is extremely limited. Timely and accurate prediction of SCD using new electronic techn...

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Main Authors: G. Tatsis, G. Baldoumas, V. Christofilakis, P. Kostarakis, P. A. Varotsos, N. V. Sarlis, E. S. Skordas, A. Bechlioulis, L. K. Michalis, K. K. Naka
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Electronics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/felec.2023.1315132/full
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author G. Tatsis
G. Baldoumas
V. Christofilakis
P. Kostarakis
P. A. Varotsos
N. V. Sarlis
E. S. Skordas
A. Bechlioulis
L. K. Michalis
K. K. Naka
author_facet G. Tatsis
G. Baldoumas
V. Christofilakis
P. Kostarakis
P. A. Varotsos
N. V. Sarlis
E. S. Skordas
A. Bechlioulis
L. K. Michalis
K. K. Naka
author_sort G. Tatsis
collection DOAJ
description Sudden cardiac death (SCD) is one of the leading causes of death worldwide. Many individuals have no cardiovascular symptoms before the SCD event. As a result, the ability to identify the risk before such an event is extremely limited. Timely and accurate prediction of SCD using new electronic technologies is greatly needed. In this work, a new innovative e-health cloud-based system is presented that allows a stratification of SCD risk based on the method of natural time entropy variability analysis. This innovative, non-invasive system can be used easily in any setting. The e-health cloud-based system was evaluated using data from a total of 203 individuals, patients with chronic heart failure (CHF) who are at high risk of SCD and age-matched healthy controls. Statistical analysis was performed in two-time windows of different duration; the first-time window had a duration of 20 min, while the second was 10 min. Employing modern methods of machine learning, classifiers for the discrimination of CHF patients from the healthy controls were obtained for the first as well as the second (half-time) window. The results indicated a very good separation between the two groups, even from samples taken in a 10-min time window. Larger studies are needed to further validate this novel e-health cloud-based system before its use in everyday clinical practice.
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spelling doaj.art-1f236536fd8b45d8a47a4501fefada002023-12-22T04:31:08ZengFrontiers Media S.A.Frontiers in Electronics2673-58572023-12-01410.3389/felec.2023.13151321315132A new e-health cloud-based system for cardiovascular risk assessmentG. Tatsis0G. Baldoumas1V. Christofilakis2P. Kostarakis3P. A. Varotsos4N. V. Sarlis5E. S. Skordas6A. Bechlioulis7L. K. Michalis8K. K. Naka9Electronics-Telecommunications and Applications Laboratory, Physics Department, University of Ioannina, Ioannina, GreeceElectronics-Telecommunications and Applications Laboratory, Physics Department, University of Ioannina, Ioannina, GreeceElectronics-Telecommunications and Applications Laboratory, Physics Department, University of Ioannina, Ioannina, GreeceElectronics-Telecommunications and Applications Laboratory, Physics Department, University of Ioannina, Ioannina, GreeceSection of Condensed Matter Physics, Department of Physics, National and Kapodistrian University of Athens, Athens, GreeceSection of Condensed Matter Physics, Department of Physics, National and Kapodistrian University of Athens, Athens, GreeceSection of Condensed Matter Physics, Department of Physics, National and Kapodistrian University of Athens, Athens, Greece2nd Department of Cardiology and Michaelidion Cardiac Center, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece2nd Department of Cardiology and Michaelidion Cardiac Center, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece2nd Department of Cardiology and Michaelidion Cardiac Center, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, GreeceSudden cardiac death (SCD) is one of the leading causes of death worldwide. Many individuals have no cardiovascular symptoms before the SCD event. As a result, the ability to identify the risk before such an event is extremely limited. Timely and accurate prediction of SCD using new electronic technologies is greatly needed. In this work, a new innovative e-health cloud-based system is presented that allows a stratification of SCD risk based on the method of natural time entropy variability analysis. This innovative, non-invasive system can be used easily in any setting. The e-health cloud-based system was evaluated using data from a total of 203 individuals, patients with chronic heart failure (CHF) who are at high risk of SCD and age-matched healthy controls. Statistical analysis was performed in two-time windows of different duration; the first-time window had a duration of 20 min, while the second was 10 min. Employing modern methods of machine learning, classifiers for the discrimination of CHF patients from the healthy controls were obtained for the first as well as the second (half-time) window. The results indicated a very good separation between the two groups, even from samples taken in a 10-min time window. Larger studies are needed to further validate this novel e-health cloud-based system before its use in everyday clinical practice.https://www.frontiersin.org/articles/10.3389/felec.2023.1315132/fullnatural time analysiselectrocardiographyphotoplethysmographychronic heart failuresudden cardiac death
spellingShingle G. Tatsis
G. Baldoumas
V. Christofilakis
P. Kostarakis
P. A. Varotsos
N. V. Sarlis
E. S. Skordas
A. Bechlioulis
L. K. Michalis
K. K. Naka
A new e-health cloud-based system for cardiovascular risk assessment
Frontiers in Electronics
natural time analysis
electrocardiography
photoplethysmography
chronic heart failure
sudden cardiac death
title A new e-health cloud-based system for cardiovascular risk assessment
title_full A new e-health cloud-based system for cardiovascular risk assessment
title_fullStr A new e-health cloud-based system for cardiovascular risk assessment
title_full_unstemmed A new e-health cloud-based system for cardiovascular risk assessment
title_short A new e-health cloud-based system for cardiovascular risk assessment
title_sort new e health cloud based system for cardiovascular risk assessment
topic natural time analysis
electrocardiography
photoplethysmography
chronic heart failure
sudden cardiac death
url https://www.frontiersin.org/articles/10.3389/felec.2023.1315132/full
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