Radiosynovectomy in rheumatic diseases
Radiosynovectomy is a safe and repeatable treatment method of chronic synovitis with synovial overgrowth and refractory chronic or acute inflammatory joint effusion. It consist in the intraarticular administration of a radioactive isotope in the form of a colloid causing the extinguishing of acti...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2014-09-01
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| Series: | Journal of Ultrasonography |
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| Online Access: | http://jultrason.pl/index.php/issues/volume-14-no-58/radiosynovectomy-in-rheumatic-diseases?aid=266 |
| _version_ | 1818176779175591936 |
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| author | Jarosław B. Ćwikła Piotr Żbikowski Brygida Kwiatkowska John R. Buscombe Iwona Sudoł-Szopińska |
| author_facet | Jarosław B. Ćwikła Piotr Żbikowski Brygida Kwiatkowska John R. Buscombe Iwona Sudoł-Szopińska |
| author_sort | Jarosław B. Ćwikła |
| collection | DOAJ |
| description | Radiosynovectomy is a safe and repeatable treatment method of chronic synovitis with
synovial overgrowth and refractory chronic or acute inflammatory joint effusion. It consist
in the intraarticular administration of a radioactive isotope in the form of a colloid
causing the extinguishing of active synovitis. The radiocolloid causes permanent irradiation
of the synovium with beta ray electron beams, which ultimately leads to its fibrosis
and extinguishes the inflammatory process destroying the joint.
The main indications for radiosynovectomy include chronic and acute arthritis in the
course of systemic diseases, intraarticular bleeding in hemorrhagic diatheses (hemophilia),
selected cases of osteoarthritis, recurrent effusions following surgery, e.g. arthroplasty,
or other iatrogenic post-surgery complications causing arthritis. Radiosynovectomy
is also performed in pigmented villonodular synovitis and crystal synovitis. The most
common method used to determine the eligibility for radiosynovectomy is an ultrasound,
which shows the location and activity of the thickened synovium. The administration of
a radiocolloid into the joint, sheath or bursa should also be performed under the control
of the ultrasound image, as this ensures a precise location of the puncture needle and
full control of the isotope administration process. Clinical efficacy of radiosynovectomy
depends on the proper qualification of patients for the procedure. The success rate of
radiosynovectomy in common indications is 65–80%. It is confirmed by the visualization
of avascular (fibrotic) synovium in follow-up ultrasound tests. The aim of this article is to
present techniques and indications for the radiosynovectomy treatment. |
| first_indexed | 2024-12-11T20:21:36Z |
| format | Article |
| id | doaj.art-1f25667103324b90b33e2211f2821b70 |
| institution | Directory Open Access Journal |
| issn | 2084-8404 2451-070X |
| language | English |
| last_indexed | 2024-12-11T20:21:36Z |
| publishDate | 2014-09-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Ultrasonography |
| spelling | doaj.art-1f25667103324b90b33e2211f2821b702022-12-22T00:52:04ZengSciendoJournal of Ultrasonography2084-84042451-070X2014-09-01145824125110.15557/JoU.2014.0024Radiosynovectomy in rheumatic diseasesJarosław B. Ćwikła0Piotr Żbikowski1Brygida Kwiatkowska2John R. Buscombe3Iwona Sudoł-Szopińska4Faculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, Poland; Department of Radiology and Diagnostic Imaging, Centre of Postgraduate Medical Education, Warsaw, PolandClinical Department of Orthopedics and Traumatology, Central Clinical Hospital of the Ministry of the Interior, Warsaw, PolandEarly Arthritis Clinic, Institute of Rheumatology, Warsaw, PolandDepartment of Nuclear Medicine and PET, Addenbrooke’s Hospital, Cambridge, UKDepartment of Radiology, Institute of Rheumatology, Warsaw, Poland; Department of Diagnostic Imaging, Warsaw Medical University, PolandRadiosynovectomy is a safe and repeatable treatment method of chronic synovitis with synovial overgrowth and refractory chronic or acute inflammatory joint effusion. It consist in the intraarticular administration of a radioactive isotope in the form of a colloid causing the extinguishing of active synovitis. The radiocolloid causes permanent irradiation of the synovium with beta ray electron beams, which ultimately leads to its fibrosis and extinguishes the inflammatory process destroying the joint. The main indications for radiosynovectomy include chronic and acute arthritis in the course of systemic diseases, intraarticular bleeding in hemorrhagic diatheses (hemophilia), selected cases of osteoarthritis, recurrent effusions following surgery, e.g. arthroplasty, or other iatrogenic post-surgery complications causing arthritis. Radiosynovectomy is also performed in pigmented villonodular synovitis and crystal synovitis. The most common method used to determine the eligibility for radiosynovectomy is an ultrasound, which shows the location and activity of the thickened synovium. The administration of a radiocolloid into the joint, sheath or bursa should also be performed under the control of the ultrasound image, as this ensures a precise location of the puncture needle and full control of the isotope administration process. Clinical efficacy of radiosynovectomy depends on the proper qualification of patients for the procedure. The success rate of radiosynovectomy in common indications is 65–80%. It is confirmed by the visualization of avascular (fibrotic) synovium in follow-up ultrasound tests. The aim of this article is to present techniques and indications for the radiosynovectomy treatment.http://jultrason.pl/index.php/issues/volume-14-no-58/radiosynovectomy-in-rheumatic-diseases?aid=266radiosynovectomysynovitisarthritisrheumatoid arthritisosteoarthritis |
| spellingShingle | Jarosław B. Ćwikła Piotr Żbikowski Brygida Kwiatkowska John R. Buscombe Iwona Sudoł-Szopińska Radiosynovectomy in rheumatic diseases Journal of Ultrasonography radiosynovectomy synovitis arthritis rheumatoid arthritis osteoarthritis |
| title | Radiosynovectomy in rheumatic diseases |
| title_full | Radiosynovectomy in rheumatic diseases |
| title_fullStr | Radiosynovectomy in rheumatic diseases |
| title_full_unstemmed | Radiosynovectomy in rheumatic diseases |
| title_short | Radiosynovectomy in rheumatic diseases |
| title_sort | radiosynovectomy in rheumatic diseases |
| topic | radiosynovectomy synovitis arthritis rheumatoid arthritis osteoarthritis |
| url | http://jultrason.pl/index.php/issues/volume-14-no-58/radiosynovectomy-in-rheumatic-diseases?aid=266 |
| work_keys_str_mv | AT jarosławbcwikła radiosynovectomyinrheumaticdiseases AT piotrzbikowski radiosynovectomyinrheumaticdiseases AT brygidakwiatkowska radiosynovectomyinrheumaticdiseases AT johnrbuscombe radiosynovectomyinrheumaticdiseases AT iwonasudołszopinska radiosynovectomyinrheumaticdiseases |