Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure

Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure

Current antibiotic testing does not include the potential influence of host cell environment on microbial susceptibility and antibiotic resistance, hindering appropriate therapeutic intervention. We devised a strategy to identify the presence of host–pathogen interactions that alter antibiotic effic...

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Bibliographic Details
Main Authors: Jessica Z. Kubicek-Sutherland, Douglas M. Heithoff, Selvi C. Ersoy, William R. Shimp, John K. House, Jamey D. Marth, Jeffrey W. Smith, Michael J. Mahan
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:EBioMedicine
Subjects:
Antibiotic resistance
MIC testing
Antibiotic-resistant mutants
Multidrug-resistant pathogens
Antimicrobial therapy
Antibiotic susceptibility testing
Salmonella
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415301055

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http://www.sciencedirect.com/science/article/pii/S2352396415301055

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