Development of a Multi-Epitope Universal mRNA Vaccine Candidate for Monkeypox, Smallpox, and Vaccinia Viruses: Design and In Silico Analyses

Development of a Multi-Epitope Universal mRNA Vaccine Candidate for Monkeypox, Smallpox, and Vaccinia Viruses: Design and In Silico Analyses

Notwithstanding the presence of a smallpox vaccine that is effective against monkeypox (mpox), developing a universal vaccine candidate against monkeypox virus (MPXV) is highly required as the mpox multi-country outbreak has increased global concern. MPXV, along with variola virus (VARV) and vaccini...

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Bibliographic Details
Main Authors: Nino Rcheulishvili, Jiawei Mao, Dimitri Papukashvili, Shunping Feng, Cong Liu, Xidan Yang, Jihui Lin, Yunjiao He, Peng George Wang
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Viruses
Subjects:
monkeypox
mpox
MPXV
universal vaccine
multi-epitope mRNA vaccine
immunoinformatics
Online Access:https://www.mdpi.com/1999-4915/15/5/1120

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