Therapeutic Targeting of the Anaplastic Lymphoma Kinase (ALK) in Neuroblastoma—A Comprehensive Update

Therapeutic Targeting of the Anaplastic Lymphoma Kinase (ALK) in Neuroblastoma—A Comprehensive Update

Neuroblastoma (NBL) is an embryonic malignancy of the sympathetic nervous system and mostly affects children under the age of five. NBL is highly heterogeneous and ranges from spontaneously regressing to highly aggressive disease. One of the risk factors for poor prognosis are aberrations in the rec...

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Bibliographic Details
Main Authors:	Annette K. Brenner, Maria W. Gunnes
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Series:	Pharmaceutics
Subjects:	neuroblastoma anaplastic lymphoma kinase point mutations monotherapy combinatory therapy drug resistance
Online Access:	https://www.mdpi.com/1999-4923/13/9/1427

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