Improving the Efficacy of Cisplatin using Niosome Nanoparticles Against Human Breast Cancer Cell Line BT-20 : An In Vitro Study
Objective: Today, cancer is one the most important challenges in modern medicine. Meanwhile, breast cancer is one of the most common causes of mortality among cancers. The initial response to the treatment and then becoming resistant to the cisplatin is one of basal challenges of treatment of breast...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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West Asia Organization for Cancer Prevention
2017-06-01
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| Series: | Asian Pacific Journal of Cancer Biology |
| Subjects: | |
| Online Access: | http://www.waocp.com/journal/index.php/apjcb/article/view/213 |
| _version_ | 1827370373538119680 |
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| author | Leila Kanaani Maral Mazloumi Tabrizi Azim Akbarzadeh Khiyavi Iraj Javadi |
| author_facet | Leila Kanaani Maral Mazloumi Tabrizi Azim Akbarzadeh Khiyavi Iraj Javadi |
| author_sort | Leila Kanaani |
| collection | DOAJ |
| description | Objective: Today, cancer is one the most important challenges in modern medicine. Meanwhile, breast cancer is one of the most common causes of mortality among cancers. The initial response to the treatment and then becoming resistant to the cisplatin is one of basal challenges of treatment of breast cancer. Recently, using nanotechnology including drug nanocarrier named niosome can decrease adverse effects and increase the efficiency of treatment.
Material and Methods: The aim of this research was to investigate using niosome nanoparticles containing cisplatin and investigation of their lethal effect on breast cancer cell line.
Results: We found that using niosome nanoparticles can provide a suitable formulation of cisplatin drug.
Conclusion: The efficiency of nanoniosome cisplatin was more than free drug, decreasing the administered dose and therefore the damage to other tissues. |
| first_indexed | 2024-03-08T10:13:22Z |
| format | Article |
| id | doaj.art-1f2b34bb2ab24f729af684572606be7f |
| institution | Directory Open Access Journal |
| issn | 2538-4635 |
| language | English |
| last_indexed | 2024-03-08T10:13:22Z |
| publishDate | 2017-06-01 |
| publisher | West Asia Organization for Cancer Prevention |
| record_format | Article |
| series | Asian Pacific Journal of Cancer Biology |
| spelling | doaj.art-1f2b34bb2ab24f729af684572606be7f2024-01-29T05:47:43ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Cancer Biology2538-46352017-06-0122272910.31557/apjcb.2017.2.2.27-29213Improving the Efficacy of Cisplatin using Niosome Nanoparticles Against Human Breast Cancer Cell Line BT-20 : An In Vitro StudyLeila KanaaniMaral Mazloumi TabriziAzim Akbarzadeh KhiyaviIraj JavadiObjective: Today, cancer is one the most important challenges in modern medicine. Meanwhile, breast cancer is one of the most common causes of mortality among cancers. The initial response to the treatment and then becoming resistant to the cisplatin is one of basal challenges of treatment of breast cancer. Recently, using nanotechnology including drug nanocarrier named niosome can decrease adverse effects and increase the efficiency of treatment. Material and Methods: The aim of this research was to investigate using niosome nanoparticles containing cisplatin and investigation of their lethal effect on breast cancer cell line. Results: We found that using niosome nanoparticles can provide a suitable formulation of cisplatin drug. Conclusion: The efficiency of nanoniosome cisplatin was more than free drug, decreasing the administered dose and therefore the damage to other tissues.http://www.waocp.com/journal/index.php/apjcb/article/view/213nanoniosome- cisplatin- breast cancer |
| spellingShingle | Leila Kanaani Maral Mazloumi Tabrizi Azim Akbarzadeh Khiyavi Iraj Javadi Improving the Efficacy of Cisplatin using Niosome Nanoparticles Against Human Breast Cancer Cell Line BT-20 : An In Vitro Study Asian Pacific Journal of Cancer Biology nanoniosome- cisplatin- breast cancer |
| title | Improving the Efficacy of Cisplatin using Niosome Nanoparticles Against Human Breast Cancer Cell Line BT-20 : An In Vitro Study |
| title_full | Improving the Efficacy of Cisplatin using Niosome Nanoparticles Against Human Breast Cancer Cell Line BT-20 : An In Vitro Study |
| title_fullStr | Improving the Efficacy of Cisplatin using Niosome Nanoparticles Against Human Breast Cancer Cell Line BT-20 : An In Vitro Study |
| title_full_unstemmed | Improving the Efficacy of Cisplatin using Niosome Nanoparticles Against Human Breast Cancer Cell Line BT-20 : An In Vitro Study |
| title_short | Improving the Efficacy of Cisplatin using Niosome Nanoparticles Against Human Breast Cancer Cell Line BT-20 : An In Vitro Study |
| title_sort | improving the efficacy of cisplatin using niosome nanoparticles against human breast cancer cell line bt 20 an in vitro study |
| topic | nanoniosome- cisplatin- breast cancer |
| url | http://www.waocp.com/journal/index.php/apjcb/article/view/213 |
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