Acute phase serum proteins in diabetic retinopathy
The serum concentration of various acute phase reactants were studied in patients with non-insulin dependent diabetes mellitus with and without retinopathy and in control subjects. The serum levels of haptoglobin was elevated in diabetics with retinopathy and the levels were highest in those with pr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
1996-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=1996;volume=44;issue=2;spage=83;epage=85;aulast=Rema |
| _version_ | 1811212396302172160 |
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| author | Rema M Mohan V Snehalatha C |
| author_facet | Rema M Mohan V Snehalatha C |
| author_sort | Rema M |
| collection | DOAJ |
| description | The serum concentration of various acute phase reactants were studied in patients with non-insulin dependent diabetes mellitus with and without retinopathy and in control subjects. The serum levels of haptoglobin was elevated in diabetics with retinopathy and the levels were highest in those with proliferative diabetic retinopathy. The levels of serum albumin, alpha-1 acid glycoprotein, alpha-1 antitrypsin and caeruloplasmin were not significantly different between the patients with retinopathy and controls. Haptoglobin increases serum viscosity and this could be the mechanism by which it plays a role in pathogenesis of diabetic retinopathy. These preliminary observations need to be confirmed by studies based on larger number of patients. Longitudinal studies on acute phase reactants in various stages of development of diabetic retinopathy would also provide valuable information. |
| first_indexed | 2024-04-12T05:28:42Z |
| format | Article |
| id | doaj.art-1f2c50cbfce44b67bd7f802fabd067d5 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 |
| language | English |
| last_indexed | 2024-04-12T05:28:42Z |
| publishDate | 1996-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-1f2c50cbfce44b67bd7f802fabd067d52022-12-22T03:46:09ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381996-01-014428385Acute phase serum proteins in diabetic retinopathyRema MMohan VSnehalatha CThe serum concentration of various acute phase reactants were studied in patients with non-insulin dependent diabetes mellitus with and without retinopathy and in control subjects. The serum levels of haptoglobin was elevated in diabetics with retinopathy and the levels were highest in those with proliferative diabetic retinopathy. The levels of serum albumin, alpha-1 acid glycoprotein, alpha-1 antitrypsin and caeruloplasmin were not significantly different between the patients with retinopathy and controls. Haptoglobin increases serum viscosity and this could be the mechanism by which it plays a role in pathogenesis of diabetic retinopathy. These preliminary observations need to be confirmed by studies based on larger number of patients. Longitudinal studies on acute phase reactants in various stages of development of diabetic retinopathy would also provide valuable information.http://www.ijo.in/article.asp?issn=0301-4738;year=1996;volume=44;issue=2;spage=83;epage=85;aulast=RemaAcute phase reactants - Haptoglobin - NIDDM - Diabetic retinopathy -Viscosity. |
| spellingShingle | Rema M Mohan V Snehalatha C Acute phase serum proteins in diabetic retinopathy Indian Journal of Ophthalmology Acute phase reactants - Haptoglobin - NIDDM - Diabetic retinopathy -Viscosity. |
| title | Acute phase serum proteins in diabetic retinopathy |
| title_full | Acute phase serum proteins in diabetic retinopathy |
| title_fullStr | Acute phase serum proteins in diabetic retinopathy |
| title_full_unstemmed | Acute phase serum proteins in diabetic retinopathy |
| title_short | Acute phase serum proteins in diabetic retinopathy |
| title_sort | acute phase serum proteins in diabetic retinopathy |
| topic | Acute phase reactants - Haptoglobin - NIDDM - Diabetic retinopathy -Viscosity. |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=1996;volume=44;issue=2;spage=83;epage=85;aulast=Rema |
| work_keys_str_mv | AT remam acutephaseserumproteinsindiabeticretinopathy AT mohanv acutephaseserumproteinsindiabeticretinopathy AT snehalathac acutephaseserumproteinsindiabeticretinopathy |