A cytosolic juxtamembrane interface modulates plexin A3 oligomerization and signal transduction.
Plexins (plxns) are transmembrane (TM) receptors involved in the guidance of vascular, lymphatic vessel, and neuron growth as well as cancer metastasis. Plxn signaling results in cytosolic GTPase-activating protein activity, and previous research implicates dimerization as important for activation o...
| Үндсэн зохиолчид: | , , , |
|---|---|
| Формат: | Өгүүллэг |
| Хэл сонгох: | English |
| Хэвлэсэн: |
Public Library of Science (PLoS)
2015-01-01
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| Цуврал: | PLoS ONE |
| Онлайн хандалт: | http://europepmc.org/articles/PMC4286236?pdf=render |