Effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucoma

AIM: To compare the effect of phacoemulsification on intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXG). METHODS: A retrospective comparative case series conducted at the Glaucoma Department at the Association to Prevent Blindness in...

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Huvudupphovsmän: Jesus Jimenez-Roman, Gabriel Lazcano-Gomez, Karina Martínez-Baez, Mauricio Turati, Rosario Gulías-Cañizo, Luis F. Hernández-Zimbrón, Lenin Ochoa-De la Paz, Rubén Zamora, Roberto Gonzalez-Salinas
Materialtyp: Artikel
Språk:English
Publicerad: Press of International Journal of Ophthalmology (IJO PRESS) 2017-09-01
Serie:International Journal of Ophthalmology
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Länkar:http://www.ijo.cn/en_publish/2017/9/20170907.pdf
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author Jesus Jimenez-Roman
Gabriel Lazcano-Gomez
Karina Martínez-Baez
Mauricio Turati
Rosario Gulías-Cañizo
Luis F. Hernández-Zimbrón
Lenin Ochoa-De la Paz
Rubén Zamora
Roberto Gonzalez-Salinas
author_facet Jesus Jimenez-Roman
Gabriel Lazcano-Gomez
Karina Martínez-Baez
Mauricio Turati
Rosario Gulías-Cañizo
Luis F. Hernández-Zimbrón
Lenin Ochoa-De la Paz
Rubén Zamora
Roberto Gonzalez-Salinas
author_sort Jesus Jimenez-Roman
collection DOAJ
description AIM: To compare the effect of phacoemulsification on intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXG). METHODS: A retrospective comparative case series conducted at the Glaucoma Department at the Association to Prevent Blindness in Mexico. The study enrolled consecutive patients having phacoemulsification with intraocular lens (IOL) implantation and a diagnosis of POAG or PXG. Data about IOP values and number of glaucoma medications used was collected at baseline, 1, 3, 6 and 12mo postoperatively. RESULTS: The study enrolled 88 patients (88 eyes). After phacoemulsification, there was a statistically significant reduction in IOP values and glaucoma medications use compared to baseline in both POAG and PXG patients (P<0.001). In the POAG group, a 20% decrease in IOP values was evidenced, and a 56.5% reduction in the number of medications used at the one-year follow-up. The PXG group showed a 20.39%, and a 34.46% decrease in IOP and number of medications used, respectively. A significant difference in the mean ΔIOP (postoperative changes in IOP) was evidenced between groups (P=0.005). The reduction of the postsurgical IOP mean values in both groups, the POAG group showed a greater reduction in IOP values compared to the PXG group. CONCLUSION: In both types of glaucoma, phacoemulsification cataract surgery can result in a significant IOP reduction (20%) over a 12mo follow-up period. The number of medications used is also significantly reduced up to 12mo after surgery, especially in the PXG group.
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spelling doaj.art-1f31eea8dda34b809ab0d871b51fca252022-12-22T01:24:13ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982017-09-011091374137810.18240/ijo.2017.09.07Effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucomaJesus Jimenez-Roman0Gabriel Lazcano-Gomez1Karina Martínez-Baez2Mauricio Turati3Rosario Gulías-Cañizo4Luis F. Hernández-Zimbrón5Lenin Ochoa-De la Paz6Rubén Zamora7Roberto Gonzalez-Salinas8Glaucoma Department, Asociation to Prevent Blindness in Mexico, Mexico City 04030, MexicoGlaucoma Department, Asociation to Prevent Blindness in Mexico, Mexico City 04030, MexicoGlaucoma Department, Asociation to Prevent Blindness in Mexico, Mexico City 04030, MexicoGlaucoma Department, Asociation to Prevent Blindness in Mexico, Mexico City 04030, MexicoResearch Department, Asociation to Prevent Blindness in Mexico, Mexico City 04030, Mexico; Cell Biology Department, Advanced Research Center, I.P.N. (CINVESTAV) in Mexico City, Mexico City 07360, MexicoResearch Department, Asociation to Prevent Blindness in Mexico, Mexico City 04030, MexicoResearch Department, Asociation to Prevent Blindness in Mexico, Mexico City 04030, MexicoResearch Department, Asociation to Prevent Blindness in Mexico, Mexico City 04030, MexicoResearch Department, Asociation to Prevent Blindness in Mexico, Mexico City 04030, MexicoAIM: To compare the effect of phacoemulsification on intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXG). METHODS: A retrospective comparative case series conducted at the Glaucoma Department at the Association to Prevent Blindness in Mexico. The study enrolled consecutive patients having phacoemulsification with intraocular lens (IOL) implantation and a diagnosis of POAG or PXG. Data about IOP values and number of glaucoma medications used was collected at baseline, 1, 3, 6 and 12mo postoperatively. RESULTS: The study enrolled 88 patients (88 eyes). After phacoemulsification, there was a statistically significant reduction in IOP values and glaucoma medications use compared to baseline in both POAG and PXG patients (P<0.001). In the POAG group, a 20% decrease in IOP values was evidenced, and a 56.5% reduction in the number of medications used at the one-year follow-up. The PXG group showed a 20.39%, and a 34.46% decrease in IOP and number of medications used, respectively. A significant difference in the mean ΔIOP (postoperative changes in IOP) was evidenced between groups (P=0.005). The reduction of the postsurgical IOP mean values in both groups, the POAG group showed a greater reduction in IOP values compared to the PXG group. CONCLUSION: In both types of glaucoma, phacoemulsification cataract surgery can result in a significant IOP reduction (20%) over a 12mo follow-up period. The number of medications used is also significantly reduced up to 12mo after surgery, especially in the PXG group.http://www.ijo.cn/en_publish/2017/9/20170907.pdf1378cataract surgerypseudoexfoliation glaucomasecondary glaucomaprimary open angle glaucomaintraocular pressure
spellingShingle Jesus Jimenez-Roman
Gabriel Lazcano-Gomez
Karina Martínez-Baez
Mauricio Turati
Rosario Gulías-Cañizo
Luis F. Hernández-Zimbrón
Lenin Ochoa-De la Paz
Rubén Zamora
Roberto Gonzalez-Salinas
Effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucoma
International Journal of Ophthalmology
1378
cataract surgery
pseudoexfoliation glaucoma
secondary glaucoma
primary open angle glaucoma
intraocular pressure
title Effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucoma
title_full Effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucoma
title_fullStr Effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucoma
title_full_unstemmed Effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucoma
title_short Effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucoma
title_sort effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucoma
topic 1378
cataract surgery
pseudoexfoliation glaucoma
secondary glaucoma
primary open angle glaucoma
intraocular pressure
url http://www.ijo.cn/en_publish/2017/9/20170907.pdf
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