The Discrepancies of COVID-19 Clinical Spectrum Between Infancy and Adolescence – Two Case Reports and a Review of the Literature
A new pandemic caused by SARS-CoV-2 raised new challenges for the worldwide healthcare system, involving the pediatric field since children own certain peculiarities that caused a different reaction to this infection as compared to adults. We report two cases of COVID-19 in two pediatric patients, a...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-10-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2020.577174/full |
| _version_ | 1818300133363679232 |
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| author | Cristina Oana Mǎrginean Lorena Elena Meliţ Maria Oana Sǎsǎran |
| author_facet | Cristina Oana Mǎrginean Lorena Elena Meliţ Maria Oana Sǎsǎran |
| author_sort | Cristina Oana Mǎrginean |
| collection | DOAJ |
| description | A new pandemic caused by SARS-CoV-2 raised new challenges for the worldwide healthcare system, involving the pediatric field since children own certain peculiarities that caused a different reaction to this infection as compared to adults. We report two cases of COVID-19 in two pediatric patients, a 6-month-old male infant and a 15-year-old female teenager in order to underline the age-related differences in terms of clinical manifestations. Thus, the 6-month-old male infant was admitted in our clinic presenting fever, rhinorrhea and diarrhea for ~24 h. Taking into account that both parents presented respiratory manifestations, nasopharyngeal/oropharyngeal swab-based polymerase chain reaction tests for SARS-CoV-2 were performed, and the test came back positive for the parents and inconclusive for the infant. Nevertheless, the infection was confirmed also in the child by the second test. The symptoms resolved in the 2nd day of admission with symptomatic treatment. The 2nd case, a 15-year-old female teenager, presented to the emergency department with fever, cough and shortness of breath (O2 saturation 84%). The chest radiography pointed out multilobar impairment. The nasopharyngeal/oropharyngeal swab-based polymerase chain reaction test for SARS-CoV-2 infection was positive. She was admitted to the intensive care unit for 3 days, and the evolution was favorable with anti-viral therapy. The pediatrician's awareness regarding both asymptomatic and atypical cases is vital for decreasing the transmission of this novel life-threatening condition. |
| first_indexed | 2024-12-13T05:02:16Z |
| format | Article |
| id | doaj.art-1f33e414bbb14d08a0a7cdd803b737c2 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-12-13T05:02:16Z |
| publishDate | 2020-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-1f33e414bbb14d08a0a7cdd803b737c22022-12-21T23:58:44ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602020-10-01810.3389/fped.2020.577174577174The Discrepancies of COVID-19 Clinical Spectrum Between Infancy and Adolescence – Two Case Reports and a Review of the LiteratureCristina Oana Mǎrginean0Lorena Elena Meliţ1Maria Oana Sǎsǎran2Department of Pediatrics I, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureş, Târgu Mures, RomaniaDepartment of Pediatrics I, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureş, Târgu Mures, RomaniaDepartment of Pediatrics III, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureş, Târgu Mures, RomaniaA new pandemic caused by SARS-CoV-2 raised new challenges for the worldwide healthcare system, involving the pediatric field since children own certain peculiarities that caused a different reaction to this infection as compared to adults. We report two cases of COVID-19 in two pediatric patients, a 6-month-old male infant and a 15-year-old female teenager in order to underline the age-related differences in terms of clinical manifestations. Thus, the 6-month-old male infant was admitted in our clinic presenting fever, rhinorrhea and diarrhea for ~24 h. Taking into account that both parents presented respiratory manifestations, nasopharyngeal/oropharyngeal swab-based polymerase chain reaction tests for SARS-CoV-2 were performed, and the test came back positive for the parents and inconclusive for the infant. Nevertheless, the infection was confirmed also in the child by the second test. The symptoms resolved in the 2nd day of admission with symptomatic treatment. The 2nd case, a 15-year-old female teenager, presented to the emergency department with fever, cough and shortness of breath (O2 saturation 84%). The chest radiography pointed out multilobar impairment. The nasopharyngeal/oropharyngeal swab-based polymerase chain reaction test for SARS-CoV-2 infection was positive. She was admitted to the intensive care unit for 3 days, and the evolution was favorable with anti-viral therapy. The pediatrician's awareness regarding both asymptomatic and atypical cases is vital for decreasing the transmission of this novel life-threatening condition.https://www.frontiersin.org/articles/10.3389/fped.2020.577174/fullCOVID-19 infectionchildrenlack of symptomsatypical casespeculiarities |
| spellingShingle | Cristina Oana Mǎrginean Lorena Elena Meliţ Maria Oana Sǎsǎran The Discrepancies of COVID-19 Clinical Spectrum Between Infancy and Adolescence – Two Case Reports and a Review of the Literature Frontiers in Pediatrics COVID-19 infection children lack of symptoms atypical cases peculiarities |
| title | The Discrepancies of COVID-19 Clinical Spectrum Between Infancy and Adolescence – Two Case Reports and a Review of the Literature |
| title_full | The Discrepancies of COVID-19 Clinical Spectrum Between Infancy and Adolescence – Two Case Reports and a Review of the Literature |
| title_fullStr | The Discrepancies of COVID-19 Clinical Spectrum Between Infancy and Adolescence – Two Case Reports and a Review of the Literature |
| title_full_unstemmed | The Discrepancies of COVID-19 Clinical Spectrum Between Infancy and Adolescence – Two Case Reports and a Review of the Literature |
| title_short | The Discrepancies of COVID-19 Clinical Spectrum Between Infancy and Adolescence – Two Case Reports and a Review of the Literature |
| title_sort | discrepancies of covid 19 clinical spectrum between infancy and adolescence two case reports and a review of the literature |
| topic | COVID-19 infection children lack of symptoms atypical cases peculiarities |
| url | https://www.frontiersin.org/articles/10.3389/fped.2020.577174/full |
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