Mid–Long-Term Outcomes of Surgical Treatment of Legg-Calvè-Perthes Disease: A Systematic Review

Background: Legg–Calvè–Perthes disease (LCPD) is a common childhood disease that usually occurs in 4- to 12-year-old children. Surgical treatment consists of femoral, pelvic, or combined osteotomies. This comprehensive review aimed to investigate the mid- and long-term outcome of the surgical treatm...

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Main Authors: Alessia Caldaci, Gianluca Testa, Eleonora Dell’Agli, Marco Sapienza, Andrea Vescio, Ludovico Lucenti, Vito Pavone
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/9/8/1121
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author Alessia Caldaci
Gianluca Testa
Eleonora Dell’Agli
Marco Sapienza
Andrea Vescio
Ludovico Lucenti
Vito Pavone
author_facet Alessia Caldaci
Gianluca Testa
Eleonora Dell’Agli
Marco Sapienza
Andrea Vescio
Ludovico Lucenti
Vito Pavone
author_sort Alessia Caldaci
collection DOAJ
description Background: Legg–Calvè–Perthes disease (LCPD) is a common childhood disease that usually occurs in 4- to 12-year-old children. Surgical treatment consists of femoral, pelvic, or combined osteotomies. This comprehensive review aimed to investigate the mid- and long-term outcome of the surgical treatment. Methods: A systematic review of PubMed, Science Direct, and MEDLINE databases was performed by two independent authors, using the keywords “outcome”, “surgical treatment”, “pelvic osteotomy”, “femoral osteotomy”, and “Legg–Calvè–Perthes disease” to evaluate studies of any level of evidence that reported the surgical outcome of LCPD. The result of every stage was reviewed and approved by two senior investigators. Results: A total of 2153 articles were found. At the end of the screening, we selected 23 articles eligible for full-text reading according to the inclusion and exclusion criteria. Our analysis showed that the main prognostic factors for surgical outcome in patients with LCPD are the age at onset and the degree of initial disease severity. Conclusions: Surgical treatment in patients older than 6 years has excellent results in Herring B and B/C hips and poor results in Herring C hips, with a slight advantage for patients between 6 and 8 years old.
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spelling doaj.art-1f34020f78c341a5a67b91914efdb8f22023-12-03T13:28:05ZengMDPI AGChildren2227-90672022-07-0198112110.3390/children9081121Mid–Long-Term Outcomes of Surgical Treatment of Legg-Calvè-Perthes Disease: A Systematic ReviewAlessia Caldaci0Gianluca Testa1Eleonora Dell’Agli2Marco Sapienza3Andrea Vescio4Ludovico Lucenti5Vito Pavone6Department of General Surgery and Medical-Surgical Specialties, Section of Orthopaedics, A.O.U. Policlinico Rodolico-San Marco, University of Catania, 95123 Catania, ItalyDepartment of General Surgery and Medical-Surgical Specialties, Section of Orthopaedics, A.O.U. Policlinico Rodolico-San Marco, University of Catania, 95123 Catania, ItalyDepartment of General Surgery and Medical-Surgical Specialties, Section of Orthopaedics, A.O.U. Policlinico Rodolico-San Marco, University of Catania, 95123 Catania, ItalyDepartment of General Surgery and Medical-Surgical Specialties, Section of Orthopaedics, A.O.U. Policlinico Rodolico-San Marco, University of Catania, 95123 Catania, ItalyDepartment of General Surgery and Medical-Surgical Specialties, Section of Orthopaedics, A.O.U. Policlinico Rodolico-San Marco, University of Catania, 95123 Catania, ItalyDepartment of General Surgery and Medical-Surgical Specialties, Section of Orthopaedics, A.O.U. Policlinico Rodolico-San Marco, University of Catania, 95123 Catania, ItalyDepartment of General Surgery and Medical-Surgical Specialties, Section of Orthopaedics, A.O.U. Policlinico Rodolico-San Marco, University of Catania, 95123 Catania, ItalyBackground: Legg–Calvè–Perthes disease (LCPD) is a common childhood disease that usually occurs in 4- to 12-year-old children. Surgical treatment consists of femoral, pelvic, or combined osteotomies. This comprehensive review aimed to investigate the mid- and long-term outcome of the surgical treatment. Methods: A systematic review of PubMed, Science Direct, and MEDLINE databases was performed by two independent authors, using the keywords “outcome”, “surgical treatment”, “pelvic osteotomy”, “femoral osteotomy”, and “Legg–Calvè–Perthes disease” to evaluate studies of any level of evidence that reported the surgical outcome of LCPD. The result of every stage was reviewed and approved by two senior investigators. Results: A total of 2153 articles were found. At the end of the screening, we selected 23 articles eligible for full-text reading according to the inclusion and exclusion criteria. Our analysis showed that the main prognostic factors for surgical outcome in patients with LCPD are the age at onset and the degree of initial disease severity. Conclusions: Surgical treatment in patients older than 6 years has excellent results in Herring B and B/C hips and poor results in Herring C hips, with a slight advantage for patients between 6 and 8 years old.https://www.mdpi.com/2227-9067/9/8/1121outcomesurgical treatmentLegg–Calvè–Perthes diseasepelvic osteotomyfemoral osteotomycombined osteotomy
spellingShingle Alessia Caldaci
Gianluca Testa
Eleonora Dell’Agli
Marco Sapienza
Andrea Vescio
Ludovico Lucenti
Vito Pavone
Mid–Long-Term Outcomes of Surgical Treatment of Legg-Calvè-Perthes Disease: A Systematic Review
Children
outcome
surgical treatment
Legg–Calvè–Perthes disease
pelvic osteotomy
femoral osteotomy
combined osteotomy
title Mid–Long-Term Outcomes of Surgical Treatment of Legg-Calvè-Perthes Disease: A Systematic Review
title_full Mid–Long-Term Outcomes of Surgical Treatment of Legg-Calvè-Perthes Disease: A Systematic Review
title_fullStr Mid–Long-Term Outcomes of Surgical Treatment of Legg-Calvè-Perthes Disease: A Systematic Review
title_full_unstemmed Mid–Long-Term Outcomes of Surgical Treatment of Legg-Calvè-Perthes Disease: A Systematic Review
title_short Mid–Long-Term Outcomes of Surgical Treatment of Legg-Calvè-Perthes Disease: A Systematic Review
title_sort mid long term outcomes of surgical treatment of legg calve perthes disease a systematic review
topic outcome
surgical treatment
Legg–Calvè–Perthes disease
pelvic osteotomy
femoral osteotomy
combined osteotomy
url https://www.mdpi.com/2227-9067/9/8/1121
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AT marcosapienza midlongtermoutcomesofsurgicaltreatmentofleggcalveperthesdiseaseasystematicreview
AT andreavescio midlongtermoutcomesofsurgicaltreatmentofleggcalveperthesdiseaseasystematicreview
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