Preclinical assessment of adjunctive tPA and DNase for peritoneal dialysis associated peritonitis.

Preclinical assessment of adjunctive tPA and DNase for peritoneal dialysis associated peritonitis.

A major complication of peritoneal dialysis is the development of peritonitis, which is associated with reduced technique and patient survival. The inflammatory response elicited by infection results in a fibrin and debris-rich environment within the peritoneal cavity, which may reduce the effective...

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Bibliographic Details
Main Authors: Amanda L McGuire, Sophia C Bennett, Sally M Lansley, Natalia D Popowicz, Julius F Varano della Vergiliana, Daniel Wong, Y C Gary Lee, Aron Chakera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4351066?pdf=render

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