A TNFR2-Agonist Facilitates High Purity Expansion of Human Low Purity Treg Cells.

Regulatory T cells (Treg) are important for immune homeostasis and are considered of great interest for immunotherapy. The paucity of Treg numbers requires the need for ex vivo expansion. Although therapeutic Treg flow-sorting is feasible, most centers aiming at Treg-based therapy focus on magnetic...

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Bibliographic Details
Main Authors: Xuehui He, Sija Landman, Stijn C G Bauland, Juliette van den Dolder, Hans J P M Koenen, Irma Joosten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4880213?pdf=render