Radicicol-Mediated Inhibition of Topoisomerase VIB-VIA Activity of the Human Malaria Parasite <named-content content-type="genus-species">Plasmodium falciparum</named-content>

Radicicol-Mediated Inhibition of Topoisomerase VIB-VIA Activity of the Human Malaria Parasite <named-content content-type="genus-species">Plasmodium falciparum</named-content>

ABSTRACT Plasmodium falciparum topoisomerase VIB (TopoVIB)-TopoVIA (TopoVIB-VIA) complex can be potentially exploited as a drug target against malaria due to its absence from the human genome. Previous work in our laboratory has suggested that P. falciparum TopoVIB (PfTopoVIB) might be a target of r...

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Bibliographic Details
Main Authors: Sureshkumar Chalapareddy, Swati Chakrabarty, Mrinal Kanti Bhattacharyya, Sunanda Bhattacharyya
Format: Article
Language:English
Published: American Society for Microbiology 2016-02-01
Series:mSphere
Subjects:
Plasmodium topoisomerase VI
Plasmodium type IIB topoisomerase
radicicol
PfTopoVIB
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00025-15

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