The Evolution of Pharmacological Activities <i>Bouea macrophylla</i> Griffith In Vivo and In Vitro Study: A Review
<i>Bouea macrophylla</i> Griffith (<i>B. macrophylla)</i> is one of the many herbal plants found in Asia, and its fruit is plum mango. This plant is rich in secondary metabolites, including flavonoids, tannins, polyphenolic compounds, and many others. Due to its bioactive com...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Pharmaceuticals |
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| Online Access: | https://www.mdpi.com/1424-8247/15/2/238 |
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| author | Intan Tsamrotul Fu’adah Sri Adi Sumiwi Gofarana Wilar |
| author_facet | Intan Tsamrotul Fu’adah Sri Adi Sumiwi Gofarana Wilar |
| author_sort | Intan Tsamrotul Fu’adah |
| collection | DOAJ |
| description | <i>Bouea macrophylla</i> Griffith (<i>B. macrophylla)</i> is one of the many herbal plants found in Asia, and its fruit is plum mango. This plant is rich in secondary metabolites, including flavonoids, tannins, polyphenolic compounds, and many others. Due to its bioactive components, plum mango has powerful antioxidants that have therapeutic benefits for many common ailments, including cardiovascular disease, diabetes, and cancer. This review describes the evolution of plum mango’s phytochemical properties and pharmacological activities including in vitro and in vivo studies. The pharmacological activities of <i>B. macrophylla</i> Griffith reviewed in this article are antioxidant, anticancer, antihyperglycemic, antimicrobial, and antiphotoaging. Each of these pharmacological activities described and studied the possible cellular and molecular mechanisms of action. Interestingly, plum mango seeds show good pharmacological activity where the seed is the part of the plant that is a waste product. This can be an advantage because of its economic value as a herbal medicine. Overall, the findings described in this review aim to allow this plant to be explored and utilized more widely, especially as a new drug discovery. |
| first_indexed | 2024-03-09T21:14:43Z |
| format | Article |
| id | doaj.art-1f40f3b71ae44288a95838bdcd609576 |
| institution | Directory Open Access Journal |
| issn | 1424-8247 |
| language | English |
| last_indexed | 2024-03-09T21:14:43Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj.art-1f40f3b71ae44288a95838bdcd6095762023-11-23T21:35:15ZengMDPI AGPharmaceuticals1424-82472022-02-0115223810.3390/ph15020238The Evolution of Pharmacological Activities <i>Bouea macrophylla</i> Griffith In Vivo and In Vitro Study: A ReviewIntan Tsamrotul Fu’adah0Sri Adi Sumiwi1Gofarana Wilar2Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang, Jatinangor, Sumedang 45363, West Java, IndonesiaDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang, Jatinangor, Sumedang 45363, West Java, IndonesiaDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang, Jatinangor, Sumedang 45363, West Java, Indonesia<i>Bouea macrophylla</i> Griffith (<i>B. macrophylla)</i> is one of the many herbal plants found in Asia, and its fruit is plum mango. This plant is rich in secondary metabolites, including flavonoids, tannins, polyphenolic compounds, and many others. Due to its bioactive components, plum mango has powerful antioxidants that have therapeutic benefits for many common ailments, including cardiovascular disease, diabetes, and cancer. This review describes the evolution of plum mango’s phytochemical properties and pharmacological activities including in vitro and in vivo studies. The pharmacological activities of <i>B. macrophylla</i> Griffith reviewed in this article are antioxidant, anticancer, antihyperglycemic, antimicrobial, and antiphotoaging. Each of these pharmacological activities described and studied the possible cellular and molecular mechanisms of action. Interestingly, plum mango seeds show good pharmacological activity where the seed is the part of the plant that is a waste product. This can be an advantage because of its economic value as a herbal medicine. Overall, the findings described in this review aim to allow this plant to be explored and utilized more widely, especially as a new drug discovery.https://www.mdpi.com/1424-8247/15/2/238<i>Bouea macrophylla</i> Griffithantioxidantanticancerantihyperglycemicantimicrobialantiphotoaging |
| spellingShingle | Intan Tsamrotul Fu’adah Sri Adi Sumiwi Gofarana Wilar The Evolution of Pharmacological Activities <i>Bouea macrophylla</i> Griffith In Vivo and In Vitro Study: A Review Pharmaceuticals <i>Bouea macrophylla</i> Griffith antioxidant anticancer antihyperglycemic antimicrobial antiphotoaging |
| title | The Evolution of Pharmacological Activities <i>Bouea macrophylla</i> Griffith In Vivo and In Vitro Study: A Review |
| title_full | The Evolution of Pharmacological Activities <i>Bouea macrophylla</i> Griffith In Vivo and In Vitro Study: A Review |
| title_fullStr | The Evolution of Pharmacological Activities <i>Bouea macrophylla</i> Griffith In Vivo and In Vitro Study: A Review |
| title_full_unstemmed | The Evolution of Pharmacological Activities <i>Bouea macrophylla</i> Griffith In Vivo and In Vitro Study: A Review |
| title_short | The Evolution of Pharmacological Activities <i>Bouea macrophylla</i> Griffith In Vivo and In Vitro Study: A Review |
| title_sort | evolution of pharmacological activities i bouea macrophylla i griffith in vivo and in vitro study a review |
| topic | <i>Bouea macrophylla</i> Griffith antioxidant anticancer antihyperglycemic antimicrobial antiphotoaging |
| url | https://www.mdpi.com/1424-8247/15/2/238 |
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