Nobiletin ameliorates glucose tolerance by protecting against β-cell loss in type-2 diabetic db/db mice
Background: Nobiletin, a polymethoxy flavone contained in the peel of Citrus reticulata, has been known to have health benefits especially those related to improvement of type 2 diabetes. Our previous in vitro study demonstrated the insulinotropic and anti-apoptotic effects of nobiletin in pancreati...
Main Authors: | Yukiko K. Kaneko, Yuki Tara, Stella Amarachi Ihim, Moe Yamamoto, Megumi Kaji, Tomohisa Ishikawa |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2022-11-01
|
Series: | Phytomedicine Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667031322001464 |
Similar Items
-
Oral ingestion of Shiikuwasha extract suppresses diabetes progression in db/db mice by preserving β-cell mass
by: Megumi Kaji, et al.
Published: (2024-01-01) -
Silk Fibroin Promotes the Regeneration of Pancreatic β-Cells in the C57BL/KsJ-<i>Lepr<sup>db/db</sup></i> Mouse
by: So-young Park, et al.
Published: (2020-07-01) -
Mitochondrial Calcium Signaling in Pancreatic β-Cell
by: Anna Weiser, et al.
Published: (2021-03-01) -
The Coffee Diterpene, Kahweol, Ameliorates Pancreatic β-Cell Function in Streptozotocin (STZ)-Treated Rat INS-1 Cells through NF-kB and p-AKT/Bcl-2 Pathways
by: Waseem El-Huneidi, et al.
Published: (2021-08-01) -
Normal β-Cell <i>Glut2</i> Expression Is not Required for Regulating Glucose-Stimulated Insulin Secretion and Systemic Glucose Homeostasis in Mice
by: Siresha Bathina, et al.
Published: (2023-03-01)