Nobiletin ameliorates glucose tolerance by protecting against β-cell loss in type-2 diabetic db/db mice

Nobiletin ameliorates glucose tolerance by protecting against β-cell loss in type-2 diabetic db/db mice

Background: Nobiletin, a polymethoxy flavone contained in the peel of Citrus reticulata, has been known to have health benefits especially those related to improvement of type 2 diabetes. Our previous in vitro study demonstrated the insulinotropic and anti-apoptotic effects of nobiletin in pancreati...

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Bibliographic Details
Main Authors: Yukiko K. Kaneko, Yuki Tara, Stella Amarachi Ihim, Moe Yamamoto, Megumi Kaji, Tomohisa Ishikawa
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Phytomedicine Plus
Subjects:
Pancreatic β-cells
β-cell mass
Insulin secretion
Insulin sensitivity
Nobiletin
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031322001464

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