SEMA3C Supports Pancreatic Cancer Progression by Regulating the Autophagy Process and Tumor Immune Microenvironment

SEMA3C Supports Pancreatic Cancer Progression by Regulating the Autophagy Process and Tumor Immune Microenvironment

To date, driver genes for pancreatic cancer treatment are difficult to pursue therapeutically. Targeting mutated KRAS, the most renowned driver gene in pancreatic cancer, is an active area of study. We discovered a gene named SEMA3C was highly expressed in pancreatic cancer cell lines and patients w...

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Bibliographic Details
Main Authors: Dalin Zhang, Aaron Lindstrom, Edward J Kim, Chang-il Hwang, Madison Lee Hall, Tzu-Yin Lin, Yuanpei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
TCGA
SEMA3C
KRAS G12D
Pancreatic Cancer
Autophagy
Tumor Immune Microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.890154/full

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