A New Removable Helical Metallic Stent for the Treatment of Tracheomalacia in Children: Study in Pathological Animal Model
Background: Congenital tracheomalacia is a pathology with no consensus of medical or surgical approach. The permanent nature and the major complications associated with metallic stents have limited their use over the years. The purpose of this study was to evaluate the feasibility of a helical stent...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/22/6757 |
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| author | Sandra Lopez-Minguez Sergio Rodriguez-Zapater Cristina Bonastre Jose Rodriguez Miguel Angel De Gregorio Jose Andres Guirola Carolina Serrano-Casorran |
| author_facet | Sandra Lopez-Minguez Sergio Rodriguez-Zapater Cristina Bonastre Jose Rodriguez Miguel Angel De Gregorio Jose Andres Guirola Carolina Serrano-Casorran |
| author_sort | Sandra Lopez-Minguez |
| collection | DOAJ |
| description | Background: Congenital tracheomalacia is a pathology with no consensus of medical or surgical approach. The permanent nature and the major complications associated with metallic stents have limited their use over the years. The purpose of this study was to evaluate the feasibility of a helical stent design removal. Methods: Ten dogs diagnosed with tracheal collapse and treated with the helical stent were involved in the study. Animals were classified into three groups depending on stent indwelling time. Prior to the removal, endoscopic evaluation was performed to assess endothelization grade, mucous accumulation, and the presence of stenosis. During the removal, bleeding, fracture, or impossibility of removal were noted. After the removal, all macroscopic mucosal changes were recorded. Results: Technical success was 100%, without any complications. Complete epithelization of the stent was visualized in 7/10 animals. The removal procedure duration ranged from 2–12 min. At post-removal endoscopy, bleeding or epithelial damage, was visualized in any case. Stent fracture during removal occurred in one animal. Conclusions: The removal of a metallic stent with spiral geometry is feasible, simple, and without complications, regardless of the degree of neo-epithelialization. |
| first_indexed | 2024-03-09T18:14:27Z |
| format | Article |
| id | doaj.art-1f4726a3c9944cd397b3935f115e9c2d |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T18:14:27Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-1f4726a3c9944cd397b3935f115e9c2d2023-11-24T08:49:37ZengMDPI AGJournal of Clinical Medicine2077-03832022-11-011122675710.3390/jcm11226757A New Removable Helical Metallic Stent for the Treatment of Tracheomalacia in Children: Study in Pathological Animal ModelSandra Lopez-Minguez0Sergio Rodriguez-Zapater1Cristina Bonastre2Jose Rodriguez3Miguel Angel De Gregorio4Jose Andres Guirola5Carolina Serrano-Casorran6Department of Animal Pathology, Faculty of Veterinary, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, SpainMinimally Invasive Research Group (GITMI), University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, SpainDepartment of Animal Pathology, Faculty of Veterinary, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, SpainDepartment of Animal Pathology, Faculty of Veterinary, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, SpainMinimally Invasive Research Group (GITMI), University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, SpainMinimally Invasive Research Group (GITMI), University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, SpainDepartment of Animal Pathology, Faculty of Veterinary, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, SpainBackground: Congenital tracheomalacia is a pathology with no consensus of medical or surgical approach. The permanent nature and the major complications associated with metallic stents have limited their use over the years. The purpose of this study was to evaluate the feasibility of a helical stent design removal. Methods: Ten dogs diagnosed with tracheal collapse and treated with the helical stent were involved in the study. Animals were classified into three groups depending on stent indwelling time. Prior to the removal, endoscopic evaluation was performed to assess endothelization grade, mucous accumulation, and the presence of stenosis. During the removal, bleeding, fracture, or impossibility of removal were noted. After the removal, all macroscopic mucosal changes were recorded. Results: Technical success was 100%, without any complications. Complete epithelization of the stent was visualized in 7/10 animals. The removal procedure duration ranged from 2–12 min. At post-removal endoscopy, bleeding or epithelial damage, was visualized in any case. Stent fracture during removal occurred in one animal. Conclusions: The removal of a metallic stent with spiral geometry is feasible, simple, and without complications, regardless of the degree of neo-epithelialization.https://www.mdpi.com/2077-0383/11/22/6757animal testingnon-traumatic tracheal stent removal techniqueremovable stenttracheomalaciapediatrics |
| spellingShingle | Sandra Lopez-Minguez Sergio Rodriguez-Zapater Cristina Bonastre Jose Rodriguez Miguel Angel De Gregorio Jose Andres Guirola Carolina Serrano-Casorran A New Removable Helical Metallic Stent for the Treatment of Tracheomalacia in Children: Study in Pathological Animal Model Journal of Clinical Medicine animal testing non-traumatic tracheal stent removal technique removable stent tracheomalacia pediatrics |
| title | A New Removable Helical Metallic Stent for the Treatment of Tracheomalacia in Children: Study in Pathological Animal Model |
| title_full | A New Removable Helical Metallic Stent for the Treatment of Tracheomalacia in Children: Study in Pathological Animal Model |
| title_fullStr | A New Removable Helical Metallic Stent for the Treatment of Tracheomalacia in Children: Study in Pathological Animal Model |
| title_full_unstemmed | A New Removable Helical Metallic Stent for the Treatment of Tracheomalacia in Children: Study in Pathological Animal Model |
| title_short | A New Removable Helical Metallic Stent for the Treatment of Tracheomalacia in Children: Study in Pathological Animal Model |
| title_sort | new removable helical metallic stent for the treatment of tracheomalacia in children study in pathological animal model |
| topic | animal testing non-traumatic tracheal stent removal technique removable stent tracheomalacia pediatrics |
| url | https://www.mdpi.com/2077-0383/11/22/6757 |
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