Paper-based LRET sensor for the detection of total heavy rare-earth ions
Based on the mechanism of luminescence resonance energy transfer (LRET) and using a special single strand DNA as the recognition element, a portable paper-based sensor for the accurate detection of total heavy rare-earth ions (mainly Gd3+, Tb3+ and Dy3+) concentration was proposed. The RNA cleaving-...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Chemistry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2022.1028441/full |
| _version_ | 1811229784844271616 |
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| author | Qiang Chen Keren Tang Dengwang Luo Luodan Han ChunXiao Yu Yiping Shen Qi Lin Yiting Chen Chunyan Li Jinghua Chen Jianming Lan |
| author_facet | Qiang Chen Keren Tang Dengwang Luo Luodan Han ChunXiao Yu Yiping Shen Qi Lin Yiting Chen Chunyan Li Jinghua Chen Jianming Lan |
| author_sort | Qiang Chen |
| collection | DOAJ |
| description | Based on the mechanism of luminescence resonance energy transfer (LRET) and using a special single strand DNA as the recognition element, a portable paper-based sensor for the accurate detection of total heavy rare-earth ions (mainly Gd3+, Tb3+ and Dy3+) concentration was proposed. The RNA cleaving-DNAzyme should recognize rare-earth ions to cleave RNA on DNA duplexes linking UCNPs and AuNPs, causing UCNPs and AuNPs to approach each other, inducing LRET, which attenuated the green upconversion luminescence (UCL) triggered by the 980 nm laser. UCL was captured by a charge-coupled device (CCD) image sensor and processed with the red-green-blue (RGB) image to quantitatively analyze heavy rare-earth ions in the samples. In the range of 5–50 μmol·L-1, the sensor has good sensitivity, with the limit of detection of 1.26 μmol L−1. |
| first_indexed | 2024-04-12T10:18:52Z |
| format | Article |
| id | doaj.art-1f49dac5f91d4fdf9cb17d80ed67cb51 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-12T10:18:52Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-1f49dac5f91d4fdf9cb17d80ed67cb512022-12-22T03:37:08ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462022-10-011010.3389/fchem.2022.10284411028441Paper-based LRET sensor for the detection of total heavy rare-earth ionsQiang Chen0Keren Tang1Dengwang Luo2Luodan Han3ChunXiao Yu4Yiping Shen5Qi Lin6Yiting Chen7Chunyan Li8Jinghua Chen9Jianming Lan10College of Materials and Chemical Engineering, MinJiang University, Fuzhou, ChinaThe School of Pharmacy, Fujian Medical University, Fuzhou, ChinaCAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing, ChinaThe School of Pharmacy, Fujian Medical University, Fuzhou, ChinaThe School of Pharmacy, Fujian Medical University, Fuzhou, ChinaThe School of Pharmacy, Fujian Medical University, Fuzhou, ChinaCollege of Materials and Chemical Engineering, MinJiang University, Fuzhou, ChinaCollege of Materials and Chemical Engineering, MinJiang University, Fuzhou, ChinaThe School of Pharmacy, Fujian Medical University, Fuzhou, ChinaThe School of Pharmacy, Fujian Medical University, Fuzhou, ChinaThe School of Pharmacy, Fujian Medical University, Fuzhou, ChinaBased on the mechanism of luminescence resonance energy transfer (LRET) and using a special single strand DNA as the recognition element, a portable paper-based sensor for the accurate detection of total heavy rare-earth ions (mainly Gd3+, Tb3+ and Dy3+) concentration was proposed. The RNA cleaving-DNAzyme should recognize rare-earth ions to cleave RNA on DNA duplexes linking UCNPs and AuNPs, causing UCNPs and AuNPs to approach each other, inducing LRET, which attenuated the green upconversion luminescence (UCL) triggered by the 980 nm laser. UCL was captured by a charge-coupled device (CCD) image sensor and processed with the red-green-blue (RGB) image to quantitatively analyze heavy rare-earth ions in the samples. In the range of 5–50 μmol·L-1, the sensor has good sensitivity, with the limit of detection of 1.26 μmol L−1.https://www.frontiersin.org/articles/10.3389/fchem.2022.1028441/fullluminescence resonance energy transferDNAzymeupconversion nanoparticlesAuNPsrare-earth ions |
| spellingShingle | Qiang Chen Keren Tang Dengwang Luo Luodan Han ChunXiao Yu Yiping Shen Qi Lin Yiting Chen Chunyan Li Jinghua Chen Jianming Lan Paper-based LRET sensor for the detection of total heavy rare-earth ions Frontiers in Chemistry luminescence resonance energy transfer DNAzyme upconversion nanoparticles AuNPs rare-earth ions |
| title | Paper-based LRET sensor for the detection of total heavy rare-earth ions |
| title_full | Paper-based LRET sensor for the detection of total heavy rare-earth ions |
| title_fullStr | Paper-based LRET sensor for the detection of total heavy rare-earth ions |
| title_full_unstemmed | Paper-based LRET sensor for the detection of total heavy rare-earth ions |
| title_short | Paper-based LRET sensor for the detection of total heavy rare-earth ions |
| title_sort | paper based lret sensor for the detection of total heavy rare earth ions |
| topic | luminescence resonance energy transfer DNAzyme upconversion nanoparticles AuNPs rare-earth ions |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2022.1028441/full |
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