Impulsive Controllers Design for the Practical Stability Analysis of Gene Regulatory Networks with Distributed Delays

This paper studies gene regulatory networks (GRNs) with distributed delays. The essential concept of practical stability of the genes is introduced. We investigate the problems of practical stability and global practical exponential stability of the GRN model under an impulsive control. New practica...

Full description

Bibliographic Details
Main Authors: Jinde Cao, Trayan Stamov, Gani Stamov, Ivanka Stamova
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Fractal and Fractional
Subjects:
Online Access:https://www.mdpi.com/2504-3110/7/12/847
_version_ 1797380960069615616
author Jinde Cao
Trayan Stamov
Gani Stamov
Ivanka Stamova
author_facet Jinde Cao
Trayan Stamov
Gani Stamov
Ivanka Stamova
author_sort Jinde Cao
collection DOAJ
description This paper studies gene regulatory networks (GRNs) with distributed delays. The essential concept of practical stability of the genes is introduced. We investigate the problems of practical stability and global practical exponential stability of the GRN model under an impulsive control. New practical stability criteria are proposed by designing appropriate impulsive controllers via the Lyapunov functions approach. In the design of the impulsive controller, we consider the effect of impulsive perturbations at fixed times and distributed delays on the stability of the considered GRNs. Several numerical examples are also presented to justify the proposed criteria.
first_indexed 2024-03-08T20:45:26Z
format Article
id doaj.art-1f4e5e83b99c48d897b5c217d7350602
institution Directory Open Access Journal
issn 2504-3110
language English
last_indexed 2024-03-08T20:45:26Z
publishDate 2023-11-01
publisher MDPI AG
record_format Article
series Fractal and Fractional
spelling doaj.art-1f4e5e83b99c48d897b5c217d73506022023-12-22T14:09:57ZengMDPI AGFractal and Fractional2504-31102023-11-0171284710.3390/fractalfract7120847Impulsive Controllers Design for the Practical Stability Analysis of Gene Regulatory Networks with Distributed DelaysJinde Cao0Trayan Stamov1Gani Stamov2Ivanka Stamova3Jiangsu Provincial Key Laboratory of Networked Collective Intelligence, School of Mathematics, Southeast University, Nanjing 211189, ChinaDepartment of Engineering Design, Technical University of Sofia, 1000 Sofia, BulgariaDepartment of Mathematics, University of Texas at San Antonio, San Antonio, TX 78249, USADepartment of Mathematics, University of Texas at San Antonio, San Antonio, TX 78249, USAThis paper studies gene regulatory networks (GRNs) with distributed delays. The essential concept of practical stability of the genes is introduced. We investigate the problems of practical stability and global practical exponential stability of the GRN model under an impulsive control. New practical stability criteria are proposed by designing appropriate impulsive controllers via the Lyapunov functions approach. In the design of the impulsive controller, we consider the effect of impulsive perturbations at fixed times and distributed delays on the stability of the considered GRNs. Several numerical examples are also presented to justify the proposed criteria.https://www.mdpi.com/2504-3110/7/12/847practical stabilityimpulsesdistributed delaysLyapunov functions
spellingShingle Jinde Cao
Trayan Stamov
Gani Stamov
Ivanka Stamova
Impulsive Controllers Design for the Practical Stability Analysis of Gene Regulatory Networks with Distributed Delays
Fractal and Fractional
practical stability
impulses
distributed delays
Lyapunov functions
title Impulsive Controllers Design for the Practical Stability Analysis of Gene Regulatory Networks with Distributed Delays
title_full Impulsive Controllers Design for the Practical Stability Analysis of Gene Regulatory Networks with Distributed Delays
title_fullStr Impulsive Controllers Design for the Practical Stability Analysis of Gene Regulatory Networks with Distributed Delays
title_full_unstemmed Impulsive Controllers Design for the Practical Stability Analysis of Gene Regulatory Networks with Distributed Delays
title_short Impulsive Controllers Design for the Practical Stability Analysis of Gene Regulatory Networks with Distributed Delays
title_sort impulsive controllers design for the practical stability analysis of gene regulatory networks with distributed delays
topic practical stability
impulses
distributed delays
Lyapunov functions
url https://www.mdpi.com/2504-3110/7/12/847
work_keys_str_mv AT jindecao impulsivecontrollersdesignforthepracticalstabilityanalysisofgeneregulatorynetworkswithdistributeddelays
AT trayanstamov impulsivecontrollersdesignforthepracticalstabilityanalysisofgeneregulatorynetworkswithdistributeddelays
AT ganistamov impulsivecontrollersdesignforthepracticalstabilityanalysisofgeneregulatorynetworkswithdistributeddelays
AT ivankastamova impulsivecontrollersdesignforthepracticalstabilityanalysisofgeneregulatorynetworkswithdistributeddelays