Non-myeloid Cells are Major Contributors to Innate Immune Responses via Production of Monocyte Chemoattractant Protein- 1(MCP-1)/CCL2

Non-myeloid Cells are Major Contributors to Innate Immune Responses via Production of Monocyte Chemoattractant Protein- 1(MCP-1)/CCL2

Monocyte chemoattractant protein-1 (MCP-1)/CCL2 is a chemokine regulating the recruitment of monocytes into sites of inflammation and cancer. MCP-1 can be produced by a variety of cell types, such as macrophages, neutrophils, fibroblasts, endothelial cells and epithelial cells. Notably, macrophage...

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Bibliographic Details
Main Authors: Teizo eYoshimura, Carole eGalligan, Munehisa eTakahashi, Keqiang eChen, Mingyong eLiu, Lino eTessarollo, Ji Ming eWang
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Immunology
Subjects:
Chemokines
Inflammation
Myeloid Cells
innate immunity
gene knockout mice
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00482/full

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