Revealing role of epigenetic modifiers and DNA oxidation in cell-autonomous regulation of Cancer stem cells

Revealing role of epigenetic modifiers and DNA oxidation in cell-autonomous regulation of Cancer stem cells

Abstract Background Breast cancer cells (BCCs) can remain undetected for decades in dormancy. These quiescent cells are similar to cancer stem cells (CSCs); hence their ability to initiate tertiary metastasis. Dormancy can be regulated by components of the tissue microenvironment such as bone marrow...

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Bibliographic Details
Main Authors: Alejandra I. Ferrer-Diaz, Garima Sinha, Andrew Petryna, Ruth Gonzalez-Bermejo, Yannick Kenfack, Oluwadamilola Adetayo, Shyam A. Patel, Anupama Hooda-Nehra, Pranela Rameshwar
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell Communication and Signaling
Subjects:
Breast cancer
Dormancy
Epigenome
Resistance
Cancer stem cell
Online Access:https://doi.org/10.1186/s12964-024-01512-1

Internet

https://doi.org/10.1186/s12964-024-01512-1

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