Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles

Abstract Super-resolution microscopic imaging employing upconversion nanoparticles is applied to reveal the surface heterogeneity of tumor cell-derived small extracellular vesicles, i.e., exosome. The number of surface antigens of every extracellular vesicles can be quantified by both the high imagi...

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Bibliographic Details
Main Authors: Rui Pu, Qiuqiang Zhan
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Light: Science & Applications
Online Access:https://doi.org/10.1038/s41377-023-01106-5

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