Endothelial Microparticles in Uremia: Biomarkers and Potential Therapeutic Targets

Endothelial Microparticles in Uremia: Biomarkers and Potential Therapeutic Targets

Endothelial microparticles (EMPs) are vesicles derived from cell membranes, which contain outsourced phosphatidylserine and express adhesion molecules, such as cadherin, intercellular cell adhesion molecule-1 (ICAM-1), E-selectin, and integrins. EMPs are expressed under physiological conditions and...

Full description

Bibliographic Details
Main Authors:	Giane Favretto, Regiane Stafim da Cunha, Maria Aparecida Dalboni, Rodrigo Bueno de Oliveira, Fellype de Carvalho Barreto, Ziad A. Massy, Andréa Emilia Marques Stinghen
Format:	Article
Language:	English
Published:	MDPI AG 2019-05-01
Series:	Toxins
Subjects:	Endothelial microparticles cardiovascular disease uremia
Online Access:	https://www.mdpi.com/2072-6651/11/5/267

Similar Items

Kristaluria disertai Azotemia dan Uremia pada Kucing
by: Hary Purnamaningsih, et al.
Published: (2024-12-01)

Endothelial Microparticles as Potential Biomarkers in the Assessment of Endothelial Dysfunction in Hypercholesterolemia
by: Nik Nor Izah Nik Ibrahim, et al.
Published: (2022-06-01)

The quest for a better understanding of chronic kidney disease complications: an update on uremic toxins
by: Fellype Carvalho Barreto, et al.
Published: (2014-04-01)

A Historical Perspective on Uremia and Uremic Toxins
by: Björn Meijers, et al.
Published: (2024-05-01)

How do Uremic Toxins Affect the Endothelium?
by: Regiane Stafim da Cunha, et al.
Published: (2020-06-01)

Orofacial dyskinesia in uremia in polycystic kidney disease
by: Nidhi Arora, et al.
Published: (2023-01-01)

The role of neuroimmune and inflammation in pediatric uremia-induced neuropathy
by: Linfeng Zhu, et al.
Published: (2022-09-01)

Association of Plasma Irisin Levels with Circulating Endothelial Microparticles (EMPs) and Endothelial Progenitor Cells (EPCs) in Children Born Prematurely
by: Panagiota Markopoulou, et al.
Published: (2023-01-01)

“Noodle-like” deformity and spontaneous fracture of the lower limbs in uremia-a case report
by: Na An, et al.
Published: (2020-11-01)

[Gly14]-Humanin Ameliorates High Glucose-Induced Apoptosis by Inhibiting the Expression of MicroRNA-155 in Endothelial Microparticles
by: Shen MY, et al.
Published: (2021-05-01)

Persistent singultus due to uremia: report of a pediatric case and review of the literature Singulto (hipo) persistente provocado por uremia: Reporte de un caso pediátrico y revisión de la literatura
by: José William Cornejo Ochoa, et al.
Published: (2002-04-01)

Endothelial microparticles: A mechanosensitive regulator of vascular homeostasis and injury under shear stress
by: Shuo Feng, et al.
Published: (2022-09-01)

Racial differences in tumor necrosis factor-α-induced endothelial microparticles and interleukin-6 production
by: Brown M, et al.
Published: (2011-08-01)

Pancreas fat content, insulin homeostasis and circulating endothelial microparticles in male essential hypertensive patients
by: Verónica Alfaro‐Lara, et al.
Published: (2023-01-01)

Influence of uremia and peritoneal dialysis on mesothelial cells of the peritoneum
by: Trpinac Dušan P., et al.
Published: (2002-01-01)

Circulating microparticles and central blood pressure according to antihypertensive strategy
by: Nayara D. Massunaga, et al.
Published: (2019-11-01)

Homocysteine Aggravates Intestinal Epithelial Barrier Dysfunction in Rats with Experimental Uremia
by: Shanshan Liang, et al.
Published: (2018-10-01)

Circulating Microparticles Are Elevated in Treated HIV‐1 Infection and Are Deleterious to Endothelial Cell Function
by: Jamie G. Hijmans, et al.
Published: (2019-02-01)

Exploration of cerebral vasospasm from the perspective of microparticles
by: Yalong Gao, et al.
Published: (2022-10-01)

Epidemiologia e distribuição de lesões extrarrenais de uremia em 161 cães
by: Isadora P. Silveira, et al.
Published: (2015-06-01)

Brain Endothelial Cells Release Apical and Basolateral Microparticles in Response to Inflammatory Cytokine Stimulation: Relevance to Neuroinflammatory Stress?
by: J. Winny Yun, et al.
Published: (2019-06-01)

Uremia-Associated Ageing of the Thymus and Adaptive Immune Responses
by: Michiel GH Betjes
Published: (2020-04-01)

Sinomenine attenuates uremia vascular calcification by miR-143-5p
by: Fengyi Yu, et al.
Published: (2025-01-01)

Improved placental vascular repair in a rat preeclampsia model by implantation of endothelial progenitor cells treated with platelet microparticles
by: Zhenya Fang, et al.
Published: (2020-10-01)

Bubbles Induce Endothelial Microparticle Formation via a Calcium-Dependent Pathway Involving Flippase Inactivation and Rho Kinase Activation
by: Xuhua Yu, et al.
Published: (2018-04-01)

Acute movement disorder with bilateral basal ganglia lesions in diabetic uremia
by: Gurusidheshwar M Wali, et al.
Published: (2011-01-01)

Evaluating the Effects of Climatic Changes on Runoff of Nazloochaei River in Uremia Lake Catchment Area
by: Gholam Hossein Lakzaianpour, et al.
Published: (2016-03-01)

Endothelial activation and injury by microparticles in patients with systemic lupus erythematosus and rheumatoid arthritis
by: Laura Atehortúa, et al.
Published: (2019-01-01)

Association between indoxyl sulfate and bone histomorphometry in pre-dialysis chronic kidney disease patients
by: Fellype Carvalho Barreto, et al.
Published: (2014-09-01)

Effect of esaxerenone on the onset of aortic endothelial dysfunction and circulating microparticles in type 1 diabetic male mice
by: Kumiko Taguchi, et al.
Published: (2024-11-01)

Circulating microparticles are associated with plaque burden and cause eNOS uncoupling in patients with carotid atherosclerosis
by: Xiaowan Han, et al.
Published: (2022-11-01)

Endothelial Progenitors and Blood Microparticles: Are They Relevant to Heart Failure With Preserved Ejection Fraction?
by: Eduard Shantsila, et al.
Published: (2016-02-01)

The effects of empagliflozin vs metformin on endothelial microparticles in overweight/obese women with polycystic ovary syndrome
by: Zeeshan Javed, et al.
Published: (2020-06-01)

Risk factors for radial artery calcification in patients with and without uremia
by: Jian-bing Hao, et al.
Published: (2025-01-01)

Grculation of microparticles of lymphocytic origin at critical ischemia of the lower extremities
by: Y. S. Vinnik, et al.
Published: (2020-04-01)

Analysis of Clinical Characteristics and Influencing Factors of Gastrointestinal Dysfunction Associated with Peritoneal Dialysis in Uremia
by: LI Jing, MA Leilei, WANG Guanran, JIANG Chen, XING Haitao, YANG Hongtao
Published: (2024-06-01)

Endothelial Microparticles Derived from Primary Pulmonary Microvascular Endothelial Cells Mediate Lung Inflammation in Chronic Obstructive Pulmonary Disease by Transferring microRNA-126
by: Ma Y, et al.
Published: (2022-02-01)

MicroRNAs Clustered within the 14q32 Locus Are Associated with Endothelial Damage and Microparticle Secretion in Bicuspid Aortic Valve Disease
by: Neus Martínez-Micaelo, et al.
Published: (2017-09-01)

Research progress on the role of platelet-derived microparticles in the development of atherosclerosis
by: GUO Fang-jun, YANG Ren-qiang
Published: (2020-11-01)

Type 2 diabetes and older age contribute to elevated plasma microparticle concentrations independent of chronic stroke
by: Rian Q. Landers‐Ramos, et al.
Published: (2018-11-01)