Human decidua-derived mesenchymal stem cells differentiate into functional alveolar type II-like cells that synthesize and secrete pulmonary surfactant complexes.
Lung alveolar type II (ATII) cells are specialized in the synthesis and secretion of pulmonary surfactant, a lipid-protein complex that reduces surface tension to minimize the work of breathing. Surfactant synthesis, assembly and secretion are closely regulated and its impairment is associated with...
Hoofdauteurs: | , , , , , |
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Formaat: | Artikel |
Taal: | English |
Gepubliceerd in: |
Public Library of Science (PLoS)
2014-01-01
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Reeks: | PLoS ONE |
Online toegang: | http://europepmc.org/articles/PMC4198213?pdf=render |