Human decidua-derived mesenchymal stem cells differentiate into functional alveolar type II-like cells that synthesize and secrete pulmonary surfactant complexes.

Lung alveolar type II (ATII) cells are specialized in the synthesis and secretion of pulmonary surfactant, a lipid-protein complex that reduces surface tension to minimize the work of breathing. Surfactant synthesis, assembly and secretion are closely regulated and its impairment is associated with...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Alejandro Cerrada, Paz de la Torre, Jesús Grande, Thomas Haller, Ana I Flores, Jesús Pérez-Gil
Formaat: Artikel
Taal:English
Gepubliceerd in: Public Library of Science (PLoS) 2014-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC4198213?pdf=render