Emerging applications of femtosecond laser fabrication in neurobiological research
As a typical micro/nano processing technique, femtosecond laser fabrication provides the opportunity to achieve delicate microstructures. The outstanding advantages, including nanoscale feature size and 3D architecting, can bridge the gap between the complexity of the central nervous system in virto...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-11-01
|
| Series: | Frontiers in Chemistry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2022.1051061/full |
| _version_ | 1811334423457562624 |
|---|---|
| author | Mingzhen Tian Mingzhen Tian Zhuo-Chen Ma Zhuo-Chen Ma Qingqing Han Qingqing Han Qian Suo Zhijun Zhang Bing Han Bing Han |
| author_facet | Mingzhen Tian Mingzhen Tian Zhuo-Chen Ma Zhuo-Chen Ma Qingqing Han Qingqing Han Qian Suo Zhijun Zhang Bing Han Bing Han |
| author_sort | Mingzhen Tian |
| collection | DOAJ |
| description | As a typical micro/nano processing technique, femtosecond laser fabrication provides the opportunity to achieve delicate microstructures. The outstanding advantages, including nanoscale feature size and 3D architecting, can bridge the gap between the complexity of the central nervous system in virto and in vivo. Up to now, various types of microstructures made by femtosecond laser are widely used in the field of neurobiological research. In this mini review, we present the recent advancement of femtosecond laser fabrication and its emerging applications in neurobiology. Typical structures are sorted out from nano, submicron to micron scale, including nanoparticles, micro/nano-actuators, and 3D scaffolds. Then, several functional units applied in neurobiological fields are summarized, such as central nervous system drug carriers, micro/nano robots and cell/tissue scaffolds. Finally, the current challenges and future perspective of integrated neurobiology research platform are discussed. |
| first_indexed | 2024-04-13T17:07:45Z |
| format | Article |
| id | doaj.art-1f5fe7bef94b4037b3cf4bdd12f9423f |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-13T17:07:45Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-1f5fe7bef94b4037b3cf4bdd12f9423f2022-12-22T02:38:23ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462022-11-011010.3389/fchem.2022.10510611051061Emerging applications of femtosecond laser fabrication in neurobiological researchMingzhen Tian0Mingzhen Tian1Zhuo-Chen Ma2Zhuo-Chen Ma3Qingqing Han4Qingqing Han5Qian Suo6Zhijun Zhang7Bing Han8Bing Han9Institute of Medical Robotics, Shanghai Jiao Tong University, Shanghai, ChinaSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaInstitute of Medical Robotics, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Automation, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaInstitute of Medical Robotics, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Automation, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaInstitute of Medical Robotics, Shanghai Jiao Tong University, Shanghai, ChinaSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaAs a typical micro/nano processing technique, femtosecond laser fabrication provides the opportunity to achieve delicate microstructures. The outstanding advantages, including nanoscale feature size and 3D architecting, can bridge the gap between the complexity of the central nervous system in virto and in vivo. Up to now, various types of microstructures made by femtosecond laser are widely used in the field of neurobiological research. In this mini review, we present the recent advancement of femtosecond laser fabrication and its emerging applications in neurobiology. Typical structures are sorted out from nano, submicron to micron scale, including nanoparticles, micro/nano-actuators, and 3D scaffolds. Then, several functional units applied in neurobiological fields are summarized, such as central nervous system drug carriers, micro/nano robots and cell/tissue scaffolds. Finally, the current challenges and future perspective of integrated neurobiology research platform are discussed.https://www.frontiersin.org/articles/10.3389/fchem.2022.1051061/fullfemtosecond laser fabricationmicro/nano-robots3D scaffoldsdrug deliverytwo-photon polymerizationmicro/nano-structures |
| spellingShingle | Mingzhen Tian Mingzhen Tian Zhuo-Chen Ma Zhuo-Chen Ma Qingqing Han Qingqing Han Qian Suo Zhijun Zhang Bing Han Bing Han Emerging applications of femtosecond laser fabrication in neurobiological research Frontiers in Chemistry femtosecond laser fabrication micro/nano-robots 3D scaffolds drug delivery two-photon polymerization micro/nano-structures |
| title | Emerging applications of femtosecond laser fabrication in neurobiological research |
| title_full | Emerging applications of femtosecond laser fabrication in neurobiological research |
| title_fullStr | Emerging applications of femtosecond laser fabrication in neurobiological research |
| title_full_unstemmed | Emerging applications of femtosecond laser fabrication in neurobiological research |
| title_short | Emerging applications of femtosecond laser fabrication in neurobiological research |
| title_sort | emerging applications of femtosecond laser fabrication in neurobiological research |
| topic | femtosecond laser fabrication micro/nano-robots 3D scaffolds drug delivery two-photon polymerization micro/nano-structures |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2022.1051061/full |
| work_keys_str_mv | AT mingzhentian emergingapplicationsoffemtosecondlaserfabricationinneurobiologicalresearch AT mingzhentian emergingapplicationsoffemtosecondlaserfabricationinneurobiologicalresearch AT zhuochenma emergingapplicationsoffemtosecondlaserfabricationinneurobiologicalresearch AT zhuochenma emergingapplicationsoffemtosecondlaserfabricationinneurobiologicalresearch AT qingqinghan emergingapplicationsoffemtosecondlaserfabricationinneurobiologicalresearch AT qingqinghan emergingapplicationsoffemtosecondlaserfabricationinneurobiologicalresearch AT qiansuo emergingapplicationsoffemtosecondlaserfabricationinneurobiologicalresearch AT zhijunzhang emergingapplicationsoffemtosecondlaserfabricationinneurobiologicalresearch AT binghan emergingapplicationsoffemtosecondlaserfabricationinneurobiologicalresearch AT binghan emergingapplicationsoffemtosecondlaserfabricationinneurobiologicalresearch |