Factors Related to Infection and Hospitalization of Covid-19, Results of the Participants of the Ravansar Non-Communicable Diseases Cohort Study in Kermanshah Province

Background and Aim: All people living in a society are not equally at risk of COVID-19 infection and hospitalization. The current study is aimed to determine the factors related to COVID-19 infection and hospitalization among participants of Ravansar Non-Communicable Disease (RaNCD) cohort study.  M...

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Main Authors: Maryam Aghajarinezhad, Yahya Salimi, Shahab Rezaeian, Ghobad Moradi, Mehdi Moradinazar, Fatemeh Khosravi Shadmani, Roya Safari_ Faramani, Mitra Darbandi, Farid Najafi
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2023-05-01
Series:پیاورد سلامت
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Online Access:http://payavard.tums.ac.ir/article-1-7266-en.pdf
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author Maryam Aghajarinezhad
Yahya Salimi
Shahab Rezaeian
Ghobad Moradi
Mehdi Moradinazar
Fatemeh Khosravi Shadmani
Roya Safari_ Faramani
Mitra Darbandi
Farid Najafi
author_facet Maryam Aghajarinezhad
Yahya Salimi
Shahab Rezaeian
Ghobad Moradi
Mehdi Moradinazar
Fatemeh Khosravi Shadmani
Roya Safari_ Faramani
Mitra Darbandi
Farid Najafi
author_sort Maryam Aghajarinezhad
collection DOAJ
description Background and Aim: All people living in a society are not equally at risk of COVID-19 infection and hospitalization. The current study is aimed to determine the factors related to COVID-19 infection and hospitalization among participants of Ravansar Non-Communicable Disease (RaNCD) cohort study.  Materials and Methods: The present study was conducted between 28th February, 2020 to 27th November, 2021. Data from the RaNCD study, morbidity and hospitalizations cases (extracted from the medical care monitoring system, SAMA system and the handwritten list of the health department) and positive serological results were used. For the case-cohort study, 626 confirmed and/or probable cases and 2107 randomly selected participants as sub-cohort were recruited. For the case-control study, 188 COVID-19 hospitalized patients from RaNCD (as cases) and 632 positive outpatients identified as controls. Data were analyzed using Cox and logistic regression, respectively.  Results: In case-cohort study, the hazard ratio of COVID-19 among people living in rural areas, in smokers and those in middle socioeconomic status was, 0.37 (0.24, 0.58), 1.50 (1.07, 2.11), as compared to the reference groups. While the hazard ratio of people aged 46-64 and those ≥65 years old, as compared to the reference group within the first year, was 3.47 (1.76, 6.86) and 6.45 (2.80, 14.85), the corresponding value after one year was 2.23 (1.13, 4.40) and 3.52 (1.53, 8.10), respectively. The hazard ratio among those with at least one comorbidity was 2.45 (1.53, 3.92) in the first year of study and after one year decreased to 1.82 (1.14, 2.92). In addition, moderate and vigorous physical activity decreased the hazard ratio. In case-control study the odds ratio of hospitalization increased by 0.03% (1.03(1.01, 1.05)) with an increase of one year in age and in people with at least three comorbidities was 2.43 (1.24, 4.73) times of those without comorbidity.      Conclusion: Overall, one year after starting the study the decrease in hazard ratio of COVID-19 was significant. Increase in age and having comorbidities are factors that increased the odds ratio of hospitalization. Such people can be considered for the next waves of COVID-19 prioritized for health care and booster vaccination.
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spelling doaj.art-1f607b4be96944048d7f3486ae6c568c2023-11-12T07:27:35ZfasTehran University of Medical Sciencesپیاورد سلامت1735-81322008-26652023-05-01172158173Factors Related to Infection and Hospitalization of Covid-19, Results of the Participants of the Ravansar Non-Communicable Diseases Cohort Study in Kermanshah ProvinceMaryam Aghajarinezhad0Yahya Salimi1Shahab Rezaeian2Ghobad Moradi3Mehdi Moradinazar4Fatemeh Khosravi Shadmani5Roya Safari_ Faramani6Mitra Darbandi7Farid Najafi8 Master of Sciences Student of Epidemiology, Student Research Committee, School of Public Health, Kermanshah University of Medical Sciences, Kermanshah, Iran Associate Professor, Department of Epidemiology, School of Public Health, Kermanshah University of Medical Sciences, Kermanshah, Iran Associate Professor, Infectious Diseases Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran Professor, Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran Assistant Professor, Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran Assistant Professor, Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran Assistant Professor, Social Development and Health Promotion Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran Master of Science in Epidemiology, Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran Professor, Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran Background and Aim: All people living in a society are not equally at risk of COVID-19 infection and hospitalization. The current study is aimed to determine the factors related to COVID-19 infection and hospitalization among participants of Ravansar Non-Communicable Disease (RaNCD) cohort study.  Materials and Methods: The present study was conducted between 28th February, 2020 to 27th November, 2021. Data from the RaNCD study, morbidity and hospitalizations cases (extracted from the medical care monitoring system, SAMA system and the handwritten list of the health department) and positive serological results were used. For the case-cohort study, 626 confirmed and/or probable cases and 2107 randomly selected participants as sub-cohort were recruited. For the case-control study, 188 COVID-19 hospitalized patients from RaNCD (as cases) and 632 positive outpatients identified as controls. Data were analyzed using Cox and logistic regression, respectively.  Results: In case-cohort study, the hazard ratio of COVID-19 among people living in rural areas, in smokers and those in middle socioeconomic status was, 0.37 (0.24, 0.58), 1.50 (1.07, 2.11), as compared to the reference groups. While the hazard ratio of people aged 46-64 and those ≥65 years old, as compared to the reference group within the first year, was 3.47 (1.76, 6.86) and 6.45 (2.80, 14.85), the corresponding value after one year was 2.23 (1.13, 4.40) and 3.52 (1.53, 8.10), respectively. The hazard ratio among those with at least one comorbidity was 2.45 (1.53, 3.92) in the first year of study and after one year decreased to 1.82 (1.14, 2.92). In addition, moderate and vigorous physical activity decreased the hazard ratio. In case-control study the odds ratio of hospitalization increased by 0.03% (1.03(1.01, 1.05)) with an increase of one year in age and in people with at least three comorbidities was 2.43 (1.24, 4.73) times of those without comorbidity.      Conclusion: Overall, one year after starting the study the decrease in hazard ratio of COVID-19 was significant. Increase in age and having comorbidities are factors that increased the odds ratio of hospitalization. Such people can be considered for the next waves of COVID-19 prioritized for health care and booster vaccination.http://payavard.tums.ac.ir/article-1-7266-en.pdfcase-cohortcase-controlhospitalizationextended cox regressioncovid-19
spellingShingle Maryam Aghajarinezhad
Yahya Salimi
Shahab Rezaeian
Ghobad Moradi
Mehdi Moradinazar
Fatemeh Khosravi Shadmani
Roya Safari_ Faramani
Mitra Darbandi
Farid Najafi
Factors Related to Infection and Hospitalization of Covid-19, Results of the Participants of the Ravansar Non-Communicable Diseases Cohort Study in Kermanshah Province
پیاورد سلامت
case-cohort
case-control
hospitalization
extended cox regression
covid-19
title Factors Related to Infection and Hospitalization of Covid-19, Results of the Participants of the Ravansar Non-Communicable Diseases Cohort Study in Kermanshah Province
title_full Factors Related to Infection and Hospitalization of Covid-19, Results of the Participants of the Ravansar Non-Communicable Diseases Cohort Study in Kermanshah Province
title_fullStr Factors Related to Infection and Hospitalization of Covid-19, Results of the Participants of the Ravansar Non-Communicable Diseases Cohort Study in Kermanshah Province
title_full_unstemmed Factors Related to Infection and Hospitalization of Covid-19, Results of the Participants of the Ravansar Non-Communicable Diseases Cohort Study in Kermanshah Province
title_short Factors Related to Infection and Hospitalization of Covid-19, Results of the Participants of the Ravansar Non-Communicable Diseases Cohort Study in Kermanshah Province
title_sort factors related to infection and hospitalization of covid 19 results of the participants of the ravansar non communicable diseases cohort study in kermanshah province
topic case-cohort
case-control
hospitalization
extended cox regression
covid-19
url http://payavard.tums.ac.ir/article-1-7266-en.pdf
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