Clinical Characteristics and Pathogenic Gene Identification in Chinese Patients With Paget’s Disease of Bone

Clinical Characteristics and Pathogenic Gene Identification in Chinese Patients With Paget’s Disease of Bone

ObjectiveTo evaluate the clinical features of sporadic Paget’s disease of bone (PDB) in China and further explore the underlying genetic abnormalities of the disease.MethodsClinical characteristics, biochemical indices, bone turnover markers and radiographic examinations of the patients were collect...

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Bibliographic Details
Main Authors: Xiaohui Tao, Li Liu, Xingguang Yang, Zhe Wei, Zhongzhong Chen, Ge Zhang, Zhenlin Zhang, Hua Yue
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Endocrinology
Subjects:
Paget’s disease of bone
clinical characteristics
SQSTM1
whole-exome sequencing (WES)
disease-causing gene
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.850462/full

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