Safety and efficacy of percutaneous closure of perimembranous ventricular septal defects in children: Review of the results at Inkosi Albert Luthuli Central Hospital
Background/Hypothesis: Ventricular septal defect (VSD) is the most common congenital cardiac lesion. Surgical closure is the gold standard, but in an isolated perimembranous ventricular septal defect (PMVSD), percutaneous closure is an attractive alternative, particularly in a limited resource...
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| Format: | Article |
| Language: | English |
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South African Heart Association
2019-04-01
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| Series: | SA Heart Journal |
| Subjects: | |
| Online Access: | https://www.journals.ac.za/index.php/SAHJ/article/view/3407 |
| _version_ | 1818535374832533504 |
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| author | Bosman, Marelize Hoosen, Ebrahim Degiovanni, Joseph |
| author_facet | Bosman, Marelize Hoosen, Ebrahim Degiovanni, Joseph |
| author_sort | Bosman, Marelize |
| collection | DOAJ |
| description | Background/Hypothesis: Ventricular septal defect (VSD)
is the most common congenital cardiac lesion. Surgical
closure is the gold standard, but in an isolated perimembranous
ventricular septal defect (PMVSD), percutaneous
closure is an attractive alternative, particularly
in a limited resource setting. Our experience
suggests that percutaneous closure of a perimembranous
VSD, in the appropriately selected patient, is safe
and effective.
Materials and methods: We performed a retrospective
chart review of all children that underwent percutaneous
closure of a PMVSD at Inkosi Albert Luthuli
Central Hospital, from October 2010 until December
2016. Patients that had percutaneous closure of any
VSD other than PMVSD, including residual VSD postsurgical
closure, were excluded.
Results: Fourty two patients were included in our retrospective
analysis, 27 females and 15 males, with a mean
age of 6 years 6 months (Range: 2 years 9 months - 15
years 9 months). Mean follow-up was 2 years 3 months.
Successful device delivery was achieved in 97.6%. A total
of 30 patients (71.4%) had complete closure of their
defect. Eleven (26.2%) patients had a residual but
haemodynamically insignifi cant defect. Two patients
had mild aortic regurgitation post procedure. Signifi -
cant early complications included 1 patient with
moderate tricuspid regurgitation and 2 patients with
device embolisation. In one of these patients, the
embolised device was retrieved and replaced with a
larger device. In the second patient, surgical retrieval
and closure was required. No cases of heart block were
recorded.
Conclusions: In our experience, percutaneous closure of
a perimembranous ventricular septal defect in a child
appears to be safe and effective. |
| first_indexed | 2024-12-11T18:24:01Z |
| format | Article |
| id | doaj.art-1f61372621244e60b0e865cb801f4788 |
| institution | Directory Open Access Journal |
| issn | 1996-6741 2071-4602 |
| language | English |
| last_indexed | 2024-12-11T18:24:01Z |
| publishDate | 2019-04-01 |
| publisher | South African Heart Association |
| record_format | Article |
| series | SA Heart Journal |
| spelling | doaj.art-1f61372621244e60b0e865cb801f47882022-12-22T00:55:08ZengSouth African Heart AssociationSA Heart Journal1996-67412071-46022019-04-01161142010.24170/16-1-3407Safety and efficacy of percutaneous closure of perimembranous ventricular septal defects in children: Review of the results at Inkosi Albert Luthuli Central HospitalBosman, Marelize 0Hoosen, Ebrahim 1Degiovanni, Joseph 2Inkosi Albert Luthuli Central Hospital, University of Kwazulu-Natal Inkosi Albert Luthuli Central Hospital, University of Kwazulu-Natal Birmingham HospitalBackground/Hypothesis: Ventricular septal defect (VSD) is the most common congenital cardiac lesion. Surgical closure is the gold standard, but in an isolated perimembranous ventricular septal defect (PMVSD), percutaneous closure is an attractive alternative, particularly in a limited resource setting. Our experience suggests that percutaneous closure of a perimembranous VSD, in the appropriately selected patient, is safe and effective. Materials and methods: We performed a retrospective chart review of all children that underwent percutaneous closure of a PMVSD at Inkosi Albert Luthuli Central Hospital, from October 2010 until December 2016. Patients that had percutaneous closure of any VSD other than PMVSD, including residual VSD postsurgical closure, were excluded. Results: Fourty two patients were included in our retrospective analysis, 27 females and 15 males, with a mean age of 6 years 6 months (Range: 2 years 9 months - 15 years 9 months). Mean follow-up was 2 years 3 months. Successful device delivery was achieved in 97.6%. A total of 30 patients (71.4%) had complete closure of their defect. Eleven (26.2%) patients had a residual but haemodynamically insignifi cant defect. Two patients had mild aortic regurgitation post procedure. Signifi - cant early complications included 1 patient with moderate tricuspid regurgitation and 2 patients with device embolisation. In one of these patients, the embolised device was retrieved and replaced with a larger device. In the second patient, surgical retrieval and closure was required. No cases of heart block were recorded. Conclusions: In our experience, percutaneous closure of a perimembranous ventricular septal defect in a child appears to be safe and effective.https://www.journals.ac.za/index.php/SAHJ/article/view/3407Ventricular septal defectperimembraneous ventricular septal defect; percutaneous closureperimembraneous ventricular septal defectpercutaneous closure |
| spellingShingle | Bosman, Marelize Hoosen, Ebrahim Degiovanni, Joseph Safety and efficacy of percutaneous closure of perimembranous ventricular septal defects in children: Review of the results at Inkosi Albert Luthuli Central Hospital SA Heart Journal Ventricular septal defect perimembraneous ventricular septal defect; percutaneous closure perimembraneous ventricular septal defect percutaneous closure |
| title | Safety and efficacy of percutaneous closure of perimembranous ventricular septal defects in children: Review of the results at Inkosi Albert Luthuli Central Hospital |
| title_full | Safety and efficacy of percutaneous closure of perimembranous ventricular septal defects in children: Review of the results at Inkosi Albert Luthuli Central Hospital |
| title_fullStr | Safety and efficacy of percutaneous closure of perimembranous ventricular septal defects in children: Review of the results at Inkosi Albert Luthuli Central Hospital |
| title_full_unstemmed | Safety and efficacy of percutaneous closure of perimembranous ventricular septal defects in children: Review of the results at Inkosi Albert Luthuli Central Hospital |
| title_short | Safety and efficacy of percutaneous closure of perimembranous ventricular septal defects in children: Review of the results at Inkosi Albert Luthuli Central Hospital |
| title_sort | safety and efficacy of percutaneous closure of perimembranous ventricular septal defects in children review of the results at inkosi albert luthuli central hospital |
| topic | Ventricular septal defect perimembraneous ventricular septal defect; percutaneous closure perimembraneous ventricular septal defect percutaneous closure |
| url | https://www.journals.ac.za/index.php/SAHJ/article/view/3407 |
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